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Maturitas
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    • EMAS Position Statements and Clinical Guides
    • van der Schouw, Yvonne TRemove van der Schouw, Yvonne T filter
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    • Research Article12
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    • Depypere, Herman13
    • Lambrinoudaki, Irene13
    • Pérez-López, Faustino R13
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    • Schenck-Gustafsson, Karin9
    • Tremollieres, Florence9
    • Erel, C Tamer6
    • Mueck, Alfred4
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    • Maturitas13

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    • Osteoporosis3
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    EMAS Position Statements and Clincial Guides

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    • Review article

      Osteoporosis management in patients with breast cancer: EMAS position statement

      Maturitas
      Vol. 95p65–71Published online: October 6, 2016
      • Florence A. Trémollieres
      • Iuliana Ceausu
      • Herman Depypere
      • Irene Lambrinoudaki
      • Alfred Mueck
      • Faustino R. Pérez-López
      • and others
      Cited in Scopus: 33
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        Breast cancer remains the most frequent cancer in women and its incidence is increasing. However, the mortality rate has stabilized due to the progress made in the treatment of breast cancer over the last decade. In premenopausal women with hormone receptor-positive breast cancer, the goal of adjuvant treatment is to inhibit the impact of estrogen on the breast, either by blocking the estrogen receptors (with the use of tamoxifen) or by suppressing ovarian function (through surgical oophorectomy or treatment with luteinizing hormone-releasing hormone (LHRH) agonist).
      • Research Article

        A model of care for healthy menopause and ageing: EMAS position statement

        Maturitas
        Vol. 92p1–6Published online: July 8, 2016
        • Petra Stute
        • Iuliana Ceausu
        • Herman Depypere
        • Irene Lambrinoudaki
        • Alfred Mueck
        • Faustino R. Pérez-López
        • and others
        Cited in Scopus: 20
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          The menopause can now be considered to be a mid-life event as the lifespan of women continues to increase in developed countries [1]. By the year 2025, the number of postmenopausal women is expected to rise to 1.1 billion worldwide. Although not all women will experience short- or long-term problems of menopause, the high prevalence of hot flushes [2,3] and vaginal atrophy [2,4], which can last for many years, as well as osteoporosis (1 in 3 women are at risk of an osteoporotic fracture) [5], makes caring for ageing women a key issue for health professionals.
          A model of care for healthy menopause and ageing: EMAS position statement
        • Research Article

          EMAS recommendations for conditions in the workplace for menopausal women

          Maturitas
          Vol. 85p79–81Published online: December 16, 2015
          • Amanda Griffiths
          • Iuliana Ceausu
          • Herman Depypere
          • Irene Lambrinoudaki
          • Alfred Mueck
          • Faustino R. Pérez-López
          • and others
          Cited in Scopus: 31
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            Occupational health issues for older workers in general, and older women workers in particular, have often been ignored. Women form a large part of many workforces throughout Europe. The number of persons in employment in EU Member States rose between 2013 and 2014 by around 2.3 million, to 217.8 million in 2014 [1]. The employment rate for men was just over 70%, and for women, nearly 60%. A longer-term comparison shows that while the employment rate for men in 2014 was below its corresponding level ten years earlier, there was a marked increase in the proportion of women in employment.
          • Research Article

            EMAS position statement: Testosterone replacement therapy in the aging male‏

            Maturitas
            Vol. 84p94–99Published online: November 6, 2015
            • Christina Dimopoulou
            • Iuliana Ceausu
            • Herman Depypere
            • Irene Lambrinoudaki
            • Alfred Mueck
            • Faustino R. Pérez-López
            • and others
            Cited in Scopus: 40
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              Aging or the process of becoming older represents the accumulation of physical, psychological, and social changes in a human being over time, ultimately resulting in death. Late-onset hypogonadism (LOH) is characterized by decreasing circulating testosterone concentrations, in combination with a spectrum of clinical symptoms and signs, during normal aging [1].
              EMAS position statement: Testosterone replacement therapy in the aging male‏
            • Research Article

              EMAS position statement: The ten point guide to the integral management of menopausal health

              Maturitas
              Vol. 81Issue 1p88–92Published online: February 10, 2015
              • Manuel Neves-e-Castro
              • Martin Birkhauser
              • Goran Samsioe
              • Irene Lambrinoudaki
              • Santiago Palacios
              • Rafael Sanchez Borrego
              • and others
              Cited in Scopus: 73
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                With increased longevity and more women becoming centenarians, management of the menopause and postreproductive health is of growing importance as it has the potential to help promote health over several decades. Women have individual needs and the approach needs to be personalised. The position statement provides a short integral guide for all those involved in menopausal health. It covers diagnosis, screening for diseases in later life, treatment and follow-up.
              • Research Article

                EMAS position statement: Individualized breast cancer screening versus population-based mammography screening programmes

                Maturitas
                Vol. 79Issue 4p481–486Published online: September 14, 2014
                • Herman Depypere
                • Joelle Desreux
                • Faustino R. Pérez-López
                • Iuliana Ceausu
                • C. Tamer Erel
                • Irene Lambrinoudaki
                • and others
                Cited in Scopus: 19
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                  Breast cancer originates from the malignant transformation of epithelial cells within the ducts and lobules of the breast. A malignant cell is the result of the accumulation of consecutive mutations. Up or down regulation of different mutated genes will ultimately result in the heterogeneity of breast cancers [1]. Some tumors will remain in situ and will never threaten the health of women. Other tumors will become invasive and ultimately metastasize and hence be fatal when not treated. The doubling time of tumor cells is estimated between 150 and 200 days [2].
                  EMAS position statement: Individualized breast cancer screening versus population-based mammography screening programmes
                • Research Article

                  EMAS position statement: The management of postmenopausal women with vertebral osteoporotic fracture

                  Maturitas
                  Vol. 78Issue 2p131–137Published online: March 13, 2014
                  • Ioannis K. Triantafyllopoulos
                  • Kalliopi Lambropoulou-Adamidou
                  • Cleopatra C. Nacopoulos
                  • Nikolaos A. Papaioannou
                  • Iuliana Ceausu
                  • Herman Depypere
                  • and others
                  Cited in Scopus: 6
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                    Osteoporotic vertebral fractures are associated with significant morbidity, excess mortality as well as health and social service expenditure. Additionally, women with a prevalent osteoporotic vertebral fracture have a high risk of experiencing a further one within one year. It is therefore important for the physician to use a diagnostic and therapeutic algorithm for early detection and effective treatment of vertebral fractures.
                    EMAS position statement: The management of postmenopausal women with vertebral osteoporotic fracture
                  • Research Article

                    EMAS position statement: Menopause for medical students

                    Maturitas
                    Vol. 78Issue 1p67–69Published online: February 25, 2014
                    • Janet Brockie
                    • Irene Lambrinoudaki
                    • Iuliana Ceausu
                    • Herman Depypere
                    • C. Tamer Erel
                    • Faustino R. Pérez-López
                    • and others
                    Cited in Scopus: 7
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                      Discussions with patients about the menopause are becoming more complex because of women's increasing longevity, the wide range of therapeutic options, the controversies regarding menopausal hormone therapy (MHT) and the increasing use of alternative and complementary therapies. The aim of this document is to provide guidance in bullet-point style on the essential issues that medical students need to know about the stages of reproductive aging, menopause terminology, menopause and postmenopausal health [1].
                    • Research Article

                      EMAS position statement: Fertility preservation

                      Maturitas
                      Vol. 77Issue 1p85–89Published online: October 28, 2013
                      • Gesthimani Mintziori
                      • Irene Lambrinoudaki
                      • Iuliana Ceausu
                      • Herman Depypere
                      • C. Tamer Erel
                      • Faustino R. Pérez-López
                      • and others
                      Cited in Scopus: 12
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                        The increasing incidence of malignant diseases that often require gonadotoxic treatment and the tendency to become a parent later in life result in an increased need for fertility preservation.
                      • Research Article

                        EMAS position statement: Late parenthood

                        Maturitas
                        Vol. 76Issue 2p200–204Published online: July 26, 2013
                        • Gesthimani Mintziori
                        • Irene Lambrinoudaki
                        • Efstratios M. Kolibianakis
                        • Iuliana Ceausu
                        • Herman Depypere
                        • C. Tamer Erel
                        • and others
                        Cited in Scopus: 6
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                          During the last decades, couples in Europe have been delaying parenthood, mainly due to socio-demographic factors that include increased rates of university education and employment in women and poorer financial status.
                        • Research Article

                          EMAS clinical guide: Vulvar lichen sclerosus in peri and postmenopausal women

                          Maturitas
                          Vol. 74Issue 3p279–282Published online: December 26, 2012
                          • Faustino R. Pérez-López
                          • Iuliana Ceausu
                          • Herman Depypere
                          • C. Tamer Erel
                          • Irene Lambrinoudaki
                          • Margaret Rees
                          • and others
                          Cited in Scopus: 33
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                            Vulvar lichen sclerosus (LS) is a chronic inflammatory disease which affects genital labial, perineal and perianal areas, producing significant discomfort and psychological distress. However there may be diagnostic delay because of late presentation and lack of recognition of symptoms.
                          • Research Article

                            EMAS position statement: Diet and health in midlife and beyond

                            Maturitas
                            Vol. 74Issue 1p99–104Published online: November 12, 2012
                            • Irene Lambrinoudaki
                            • Iuliana Ceasu
                            • Herman Depypere
                            • Tamer Erel
                            • Margaret Rees
                            • Karin Schenck-Gustafsson
                            • and others
                            Cited in Scopus: 31
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                              There is increasing evidence that life-style factors, such as nutrition, physical activity, smoking and alcohol consumption have a profound modifying effect on the epidemiology of most major chronic conditions affecting midlife health.
                            • Research Article

                              EMAS clinical guide: Low-dose vaginal estrogens for postmenopausal vaginal atrophy

                              Maturitas
                              Vol. 73Issue 2p171–174Published online: June 29, 2012
                              • Margaret Rees
                              • Faustino R. Pérez-López
                              • Iuliana Ceasu
                              • Herman Depypere
                              • Tamer Erel
                              • Irene Lambrinoudaki
                              • and others
                              Cited in Scopus: 58
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                                Vaginal atrophy is common in postmenopausal women. This clinical guide provides the evidence for the clinical use of vaginal estrogens for this condition focussing on publications since the 2006 Cochrane systematic review. Use after breast cancer, before assessment of cervical cytology and prolapse surgery is also discussed.
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