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Maturitas
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    • EMAS Position Statements and Clinical Guides
    • Schenck-Gustafsson, KarinRemove Schenck-Gustafsson, Karin filter
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    • Research Article14

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    • Lambrinoudaki, Irene14
    • Rees, Margaret14
    • Tremollieres, Florence14
    • Pérez-López, Faustino R12
    • Depypere, Herman11
    • Erel, C Tamer11
    • Simoncini, Tommaso11
    • Ceausu, Iuliana9
    • van der Schouw, Yvonne T9
    • Gambacciani, Marco3
    • Goulis, Dimitrios G3
    • Mintziori, Gesthimani3
    • Moen, Mette H3
    • Rozenberg, Serge3
    • Vujovic, Svetlana3
    • Brincat, Marc2
    • Ceasu, Iuliana2
    • Erel, Tamer2
    • Palacios, Santiago2
    • Tarlatzis, Basil C2
    • Birkhauser, Martin1
    • Borrego, Rafael Sanchez1
    • Brincat, Mark1
    • Brockie, Janet1

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    • Maturitas14

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    • Osteoporosis3
    • Menopause2
    • Mortality2
    • Postmenopausal women2
    • 25-Hydroxyvitamin D1
    • Advanced age1
    • Advanced parental age1
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    • Breast cancer1
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    • Embryo cryopreservation1
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    • Fertility preservation1
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    EMAS Position Statements and Clincial Guides

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    • Research Article

      EMAS position statement: Non-hormonal management of menopausal vasomotor symptoms

      Maturitas
      Vol. 81Issue 3p410–413Published online: April 22, 2015
      • Gesthimani Mintziori
      • Irene Lambrinoudaki
      • Dimitrios G. Goulis
      • Iuliana Ceausu
      • Herman Depypere
      • C. Tamer Erel
      • and others
      Cited in Scopus: 63
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        To review non-hormonal therapy options for menopausal vasomotor symptoms. The current EMAS position paper aims to provide to provide guidance for managing peri- and postmenopausal women who cannot or do not wish to take menopausal hormone therapy (MHT).
      • Research Article

        EMAS position statement: The ten point guide to the integral management of menopausal health

        Maturitas
        Vol. 81Issue 1p88–92Published online: February 10, 2015
        • Manuel Neves-e-Castro
        • Martin Birkhauser
        • Goran Samsioe
        • Irene Lambrinoudaki
        • Santiago Palacios
        • Rafael Sanchez Borrego
        • and others
        Cited in Scopus: 73
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          With increased longevity and more women becoming centenarians, management of the menopause and postreproductive health is of growing importance as it has the potential to help promote health over several decades. Women have individual needs and the approach needs to be personalised. The position statement provides a short integral guide for all those involved in menopausal health. It covers diagnosis, screening for diseases in later life, treatment and follow-up.
        • Research Article

          EMAS position statement: Individualized breast cancer screening versus population-based mammography screening programmes

          Maturitas
          Vol. 79Issue 4p481–486Published online: September 14, 2014
          • Herman Depypere
          • Joelle Desreux
          • Faustino R. Pérez-López
          • Iuliana Ceausu
          • C. Tamer Erel
          • Irene Lambrinoudaki
          • and others
          Cited in Scopus: 19
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            Breast cancer originates from the malignant transformation of epithelial cells within the ducts and lobules of the breast. A malignant cell is the result of the accumulation of consecutive mutations. Up or down regulation of different mutated genes will ultimately result in the heterogeneity of breast cancers [1]. Some tumors will remain in situ and will never threaten the health of women. Other tumors will become invasive and ultimately metastasize and hence be fatal when not treated. The doubling time of tumor cells is estimated between 150 and 200 days [2].
            EMAS position statement: Individualized breast cancer screening versus population-based mammography screening programmes
          • Research Article

            EMAS position statement: Management of uterine fibroids

            Maturitas
            Vol. 79Issue 1p106–116Published online: June 10, 2014
            • Faustino R. Pérez-López
            • Lía Ornat
            • Iuliana Ceausu
            • Herman Depypere
            • C. Tamer Erel
            • Irene Lambrinoudaki
            • and others
            Cited in Scopus: 73
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              Uterine fibroids (also termed leiomyomas or myomas) are the most common tumors of the female reproductive tract.
              EMAS position statement: Management of uterine fibroids
            • Research Article

              EMAS position statement: The management of postmenopausal women with vertebral osteoporotic fracture

              Maturitas
              Vol. 78Issue 2p131–137Published online: March 13, 2014
              • Ioannis K. Triantafyllopoulos
              • Kalliopi Lambropoulou-Adamidou
              • Cleopatra C. Nacopoulos
              • Nikolaos A. Papaioannou
              • Iuliana Ceausu
              • Herman Depypere
              • and others
              Cited in Scopus: 6
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                Osteoporotic vertebral fractures are associated with significant morbidity, excess mortality as well as health and social service expenditure. Additionally, women with a prevalent osteoporotic vertebral fracture have a high risk of experiencing a further one within one year. It is therefore important for the physician to use a diagnostic and therapeutic algorithm for early detection and effective treatment of vertebral fractures.
                EMAS position statement: The management of postmenopausal women with vertebral osteoporotic fracture
              • Research Article

                EMAS position statement: Menopause for medical students

                Maturitas
                Vol. 78Issue 1p67–69Published online: February 25, 2014
                • Janet Brockie
                • Irene Lambrinoudaki
                • Iuliana Ceausu
                • Herman Depypere
                • C. Tamer Erel
                • Faustino R. Pérez-López
                • and others
                Cited in Scopus: 7
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                  Discussions with patients about the menopause are becoming more complex because of women's increasing longevity, the wide range of therapeutic options, the controversies regarding menopausal hormone therapy (MHT) and the increasing use of alternative and complementary therapies. The aim of this document is to provide guidance in bullet-point style on the essential issues that medical students need to know about the stages of reproductive aging, menopause terminology, menopause and postmenopausal health [1].
                • Research Article

                  EMAS position statement: Fertility preservation

                  Maturitas
                  Vol. 77Issue 1p85–89Published online: October 28, 2013
                  • Gesthimani Mintziori
                  • Irene Lambrinoudaki
                  • Iuliana Ceausu
                  • Herman Depypere
                  • C. Tamer Erel
                  • Faustino R. Pérez-López
                  • and others
                  Cited in Scopus: 12
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                    The increasing incidence of malignant diseases that often require gonadotoxic treatment and the tendency to become a parent later in life result in an increased need for fertility preservation.
                  • Research Article

                    EMAS position statement: Late parenthood

                    Maturitas
                    Vol. 76Issue 2p200–204Published online: July 26, 2013
                    • Gesthimani Mintziori
                    • Irene Lambrinoudaki
                    • Efstratios M. Kolibianakis
                    • Iuliana Ceausu
                    • Herman Depypere
                    • C. Tamer Erel
                    • and others
                    Cited in Scopus: 6
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                      During the last decades, couples in Europe have been delaying parenthood, mainly due to socio-demographic factors that include increased rates of university education and employment in women and poorer financial status.
                    • Research Article

                      EMAS clinical guide: Vulvar lichen sclerosus in peri and postmenopausal women

                      Maturitas
                      Vol. 74Issue 3p279–282Published online: December 26, 2012
                      • Faustino R. Pérez-López
                      • Iuliana Ceausu
                      • Herman Depypere
                      • C. Tamer Erel
                      • Irene Lambrinoudaki
                      • Margaret Rees
                      • and others
                      Cited in Scopus: 33
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                        Vulvar lichen sclerosus (LS) is a chronic inflammatory disease which affects genital labial, perineal and perianal areas, producing significant discomfort and psychological distress. However there may be diagnostic delay because of late presentation and lack of recognition of symptoms.
                      • Research Article

                        EMAS position statement: Diet and health in midlife and beyond

                        Maturitas
                        Vol. 74Issue 1p99–104Published online: November 12, 2012
                        • Irene Lambrinoudaki
                        • Iuliana Ceasu
                        • Herman Depypere
                        • Tamer Erel
                        • Margaret Rees
                        • Karin Schenck-Gustafsson
                        • and others
                        Cited in Scopus: 31
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                          There is increasing evidence that life-style factors, such as nutrition, physical activity, smoking and alcohol consumption have a profound modifying effect on the epidemiology of most major chronic conditions affecting midlife health.
                        • Research Article

                          EMAS clinical guide: Low-dose vaginal estrogens for postmenopausal vaginal atrophy

                          Maturitas
                          Vol. 73Issue 2p171–174Published online: June 29, 2012
                          • Margaret Rees
                          • Faustino R. Pérez-López
                          • Iuliana Ceasu
                          • Herman Depypere
                          • Tamer Erel
                          • Irene Lambrinoudaki
                          • and others
                          Cited in Scopus: 58
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                            Vaginal atrophy is common in postmenopausal women. This clinical guide provides the evidence for the clinical use of vaginal estrogens for this condition focussing on publications since the 2006 Cochrane systematic review. Use after breast cancer, before assessment of cervical cytology and prolapse surgery is also discussed.
                          • Research Article

                            EMAS clinical guide: Selective estrogen receptor modulators for postmenopausal osteoporosis

                            Maturitas
                            Vol. 71Issue 2p194–198Published online: November 24, 2011
                            • Santiago Palacios
                            • Mark Brincat
                            • C. Tamer Erel
                            • Marco Gambacciani
                            • Irene Lambrinoudaki
                            • Mette H. Moen
                            • and others
                            Cited in Scopus: 17
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                              Osteoporosis and the resulting fractures are major public health issues as the world population is ageing. Various therapies such as bisphosphonates, strontium ranelate and more recently denosumab are available. This clinical guide provides the evidence for the clinical use of selective estrogen modulators (SERMs) in the management of osteoporosis in postmenopausal women.
                            • Research Article

                              EMAS position statement: Vitamin D and postmenopausal health

                              Maturitas
                              Vol. 71Issue 1p83–88Published online: November 10, 2011
                              • Faustino R. Pérez-López
                              • Marc Brincat
                              • C. Tamer Erel
                              • Florence Tremollieres
                              • Marco Gambacciani
                              • Irene Lambrinoudaki
                              • and others
                              Cited in Scopus: 90
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                                There is emerging evidence on the widespread tissue effects of vitamin D.
                              • Research Article

                                EMAS position statement: Managing menopausal women with a personal or family history of VTE

                                Maturitas
                                Vol. 69Issue 2p195–198Published online: March 28, 2011
                                • Florence Tremollieres
                                • Marc Brincat
                                • C. Tamer Erel
                                • Marco Gambacciani
                                • Irene Lambrinoudaki
                                • Mette H. Moen
                                • and others
                                Cited in Scopus: 43
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                                  Venous thromboembolism (VTE), including deep venous thrombosis (DVT) and pulmonary embolism (PE), is a serious cardiovascular event whose incidence rises with increasing age.
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