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Abstract
Objective: To investigate whether information processing and attention performances are affected
by climacteric vasomotor symptoms. Methods: The study group comprised 66 healthy hysterectomized postmenopausal women. The subjects
were divided into two subgroups (high symptomatic and low symptomatic) according to
the quantity of climacteric vasomotor symptoms. Information processing was examined
using CogniSpeed, a reaction time software that separates, for example, pure controlled
processing and working memory from perceptual and motor components. Attention was
examined by using visual and auditory tasks. The role of climacteric depression as
a determinant of cognitive performance was evaluated by the Beck Depression Inventory
and dividing subjects according to self-reported climacteric mood symptoms. The effects
of serum oestrogen level and ageing on cognitive performances were also studied. Results: Cognitive performances were similar in high symptomatic and low symptomatic women.
On the Verification test younger women had shorter reaction times (P = 0.002) and on the Subtraction test they had fewer errors (P = 0.015) than older women. These tests required working memory and decision making.
Accuracy in the tests of sustained and auditory attention worsened slightly with age.
Cognitive performances neither correlated with scores on the Beck Depression scale
nor with serum oestrogen level. Climacteric mood symptoms did not impair cognitive
performance. Conclusions: Despite subjective complaints of memory impairment in association with climacteric
vasomotor symptoms, our results did not support a direct cause-and-effect relationship.
Thus, the minor deficits found in cognitive processing efficiency seem to be related
rather to age than climacteric symptoms.
Keywords
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Article info
Publication history
Accepted:
January 17,
1997
Received in revised form:
January 9,
1997
Received:
July 11,
1996
Identification
Copyright
© 1997 Published by Elsevier Inc.
