- •Due to a trend toward a more sedentary lifestyle, the middle-aged population (35–65 years) is at greater risk of developing cardiovascular disease.
- •Physical activity can prevent the initiation and progression of cardiovascular disease in middle-aged adults.
- •To prevent cardiovascular disease, the general recommendation is for at least 150 min of physical activity per week at a moderate level of intensity.
- •The type of physical activity should be adapted to the fitness level and medical condition of the individual.
- •Standardized guidelines for middle-aged individuals with cardiovascular events still need to be established.
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- Change in cardiorespiratory fitness and risk of stroke and death: long-term follow-up of healthy middle-aged men.Stroke. 2019; 50: 155-161
- Physical activity and the risk of heart failure: a systematic review and dose–response meta-analysis of prospective studies.Eur. J. Epidemiol. 2021; 36: 367-381
- Physical activity without weight loss reduces the development of cardiovascular disease risk factors – a prospective cohort study of more than one hundred thousand adults.Prog. Cardiovasc. Dis. 2019; 62: 522-530
- Physical activity and risk of cardiovascular disease among older adults.Int. J. Gerontol. 2013; 7: 133-136
- Physical activity guidelines for americans from the US department of health and human services: cardiovascular benefits and recommendations, circulation.Cardiovascular Quality and Outcomes. 2018; 11e005263
- Regular physical activity postpones age of occurrence of first-ever stroke and improves long-term outcomes.Neurol. Sci. 2021; 42: 3203-3210
- Physical and immunological aspects of exercise in chronic diseases.Immunotherapy. 2014; 6: 1145-1157
- The molecular mechanisms associated with the physiological responses to inflammation and oxidative stress in cardiovascular diseases.Biophys. Rev. 2020; 12: 947-968
- C-reactive protein and other markers of inflammation in the prediction of cardiovascular disease in women.N. Engl. J. Med. 2000; 342: 836-843
- Relationship between physical activity and inflammation among apparently healthy middle-aged and older US adults.Arch. Intern. Med. 2002; 162: 1286-1292
- Physical activity and inflammatory markers over 10 years: follow-up in men and women from the Whitehall II cohort study.Circulation. 2012; 126: 928-933
- Physical activity and reduced risk of cardiovascular events: potential mediating mechanisms.Circulation. 2007; 116: 2110-2118
- CRP and fibrinogen imply clinical outcome of patients with Type-2 diabetes and coronary artery disease.Acta Biochim. Biophys. Sin. 2017; 49: 284-285
- Inflammatory biomarkers: impact for diabetes and diabetic vascular disease.Acta Biochim. Biophys. Sin. 2015; 47: 1029-1031
- Oxidative stress triggers defective autophagy in endothelial cells: role in atherothrombosis development.Antioxidants. 2021; 10
- Training effects on ROS production determined by electron paramagnetic resonance in master swimmers.Oxidative Med. Cell. Longev. 2015; 2015804794
- The effect of continuous and interval aerobic trainings on body mass index and serum levels of ICAM-1 and VCAM-1 in men with heart failure.Rep. Health Care. 2019; 5: 44-55
- Exercise training improves functions of endothelial progenitor cells in patients with metabolic syndrome.Arq. Bras. Cardiol. 2021; 117: 108-117
- Combined aerobic and resistance training for cardiorespiratory fitness, muscle strength, and walking capacity after stroke: a systematic review and meta-analysis.J. Stroke Cerebrovasc. Dis. 2020; 29104498
- Lifetime risks for cardiovascular disease mortality by cardiorespiratory fitness levels measured at ages 45, 55, and 65 years in men: the Cooper Center longitudinal study.J. Am. Coll. Cardiol. 2011; 57: 1604-1610
- Lifestyle factors, cardiovascular disease and all-cause mortality in middle-aged and elderly women: a systematic review and meta-analysis.Eur. J. Epidemiol. 2018; 33: 831-845
- Self-rated walking pace and all-cause, cardiovascular disease and cancer mortality: individual participant pooled analysis of 50 225 walkers from 11 population British cohorts.Br. J. Sports Med. 2018; 52: 761-768
- Working Group on Cardiac Rehabilitation and Exercise Physiology and Working Group on Heart Failure. Recommendations for exercise training in chronic heart failure patients.Eur Heart J. 2001; 22: 125-135
- Prestroke physical activity could influence acute stroke severity (part of PAPSIGOT).Neurology. 2018; 91: e1461-e1467
- Sports-related sudden death in the general population.Circulation. 2011; 124: 672-681
- The effects and safety of exercise training in subjects with chronic heart failure—do elder subjects gain similar benefits?.Int. J. Gerontol. 2010; 4: 165-170
- Exercise prescription guidelines for cardiovascular disease patients in the absence of a baseline stress test.J. Cardiovasc. Dev. Dis. 2020; 7: 15
- 2020 ESC guidelines on sports cardiology and exercise in patients with cardiovascular disease: the task force on sports cardiology and exercise in patients with cardiovascular disease of the european Society of Cardiology (ESC).Eur. Heart J. 2021; 42: 17-96