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Letter to the Editor| Volume 145, P86, March 2021

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Comments on Pu et al. (2021), “The effect of a social robot intervention on sleep and motor activity of people living with dementia and chronic pain: A pilot randomized controlled trial”

      We thank Pu and colleagues for their published study evaluating the effectiveness of PARO on sleep and motor activity in people living with dementia (PLWD) and chronic pain [
      • Pu L.
      • Moyle W.
      • Jones C.
      • Todorovic M.
      The effect of a social robot intervention on sleep and motor activity of people living with dementia and chronic pain: a pilot randomized controlled trial.
      ]. Such studies generate evidence on novel non-pharmacological/psychosocial interventions for behaviours and psychological symptoms of dementia (BPSD) - a significant area of research for optimising the quality of dementia care. While we commend the authors’ efforts in conducting this research, the findings of the study should be interpreted with caution for the following reasons:
      • 1)
        Given that a large proportion of PLWD are commonly prescribed psychotropic medications (e.g., antipsychotics, antidepressants, anti-dementia drugs and opioids) [
        • Harrison S.L.
        • Sluggett J.K.
        • Lang C.
        • Whitehead C.
        • Crotty M.
        • Corlis M.
        • Wesselingh S.L.
        • Inacio M.C.
        The dispensing of psychotropic medicines to older people before and after they enter residential aged care.
        ,
        • Tan E.C.
        • Visvanathan R.
        • Hilmer S.N.
        • Vitry A.
        • Emery T.
        • Robson L.
        • Pitkälä K.
        • Ilomäki J.
        • Bell J.S.
        Analgesic use and pain in residents with and without dementia in aged care facilities: A cross-sectional study.
        ], which are known to cause (over-)sedation, how did the authors account for this confounding effect on sleep outcomes? That is, how we would know that the results were not falsely attributed to PARO rather than the prescribed concurrent medications, and hence were independent of this covariate?
      • 2)
        The Mini-Mental State Examination (MMSE) scores were <11 for 45.0 % and 71.4 % for control and intervention groups, respectively. This indicates that most of the sample had severe dementia [
        • Perneczky R.
        • Wagenpfeil S.
        • Komossa K.
        • Grimmer T.
        • Diehl J.
        • Kurz A.
        Mapping scores onto stages: mini-mental state examination and clinical dementia rating.
        ], which is characterised by a diminished capacity to report or rate pain. As noted by the authors (Table 1), the range of MMSE scores was 0–24, suggesting that some participants may have had the ability to verbalise pain [
        • Pautex S.
        • Michon A.
        • Guedira M.
        • Emond H.
        • Le Lous P.
        • Samaras D.
        • Michel J.P.
        • Herrmann F.
        • Giannakopoulos P.
        • Gold G.
        Pain in severe dementia: self-assessment or observational scales?.
        ], which is deemed the gold standard of pain assessment. However, the authors completed proxy pain assessments for the total sample.
      • 3)
        No validated (proxy) pain assessment tools were used in the study; yet pain intensity scores and categories were reported for both groups.
      • 4)
        Chronic pain (conditions) was (were) not operationally defined (or described) in the sample.

      Abbreviations:

      PLWD (people living with dementia), BPSD (behaviours and psychological symptoms of dementia), MMSE (Mini-Mental State Examination)
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      References

        • Pu L.
        • Moyle W.
        • Jones C.
        • Todorovic M.
        The effect of a social robot intervention on sleep and motor activity of people living with dementia and chronic pain: a pilot randomized controlled trial.
        Maturitas. 2021; 144: 16-22
        • Harrison S.L.
        • Sluggett J.K.
        • Lang C.
        • Whitehead C.
        • Crotty M.
        • Corlis M.
        • Wesselingh S.L.
        • Inacio M.C.
        The dispensing of psychotropic medicines to older people before and after they enter residential aged care.
        Med J Australia. 2020; 212: 309-313
        • Tan E.C.
        • Visvanathan R.
        • Hilmer S.N.
        • Vitry A.
        • Emery T.
        • Robson L.
        • Pitkälä K.
        • Ilomäki J.
        • Bell J.S.
        Analgesic use and pain in residents with and without dementia in aged care facilities: A cross-sectional study.
        Australas. J. Ageing. 2016; 35: 180-187
        • Perneczky R.
        • Wagenpfeil S.
        • Komossa K.
        • Grimmer T.
        • Diehl J.
        • Kurz A.
        Mapping scores onto stages: mini-mental state examination and clinical dementia rating.
        Am. J. Geriatr. Psychiatry. 2006; 14: 139-144
        • Pautex S.
        • Michon A.
        • Guedira M.
        • Emond H.
        • Le Lous P.
        • Samaras D.
        • Michel J.P.
        • Herrmann F.
        • Giannakopoulos P.
        • Gold G.
        Pain in severe dementia: self-assessment or observational scales?.
        J. Am. Geriatr. Soc. 2006; 54: 1040-1045

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