Highlights
- •Eurycoma longifolia and the practice of concurrent training for 6 months significantly improved the erectile function of men with androgen deficiency.
- •Eurycoma longifolia increased testosterone levels in almost 50 % of study participants.
- •Testosterone level was correlated with function in domains of men’s sexual health.
Abstract
Background
Androgen deficiency of aging males (ADAM) largely manifests as sexual symptoms. Erectile
dysfunction is one of the most common symptoms of ADAM.
Aim
To ascertain the effect of concurrent training and supplementation with Eurycoma longifolia on erectile function and testosterone levels in men with ADAM, and the association
of erectile function with levels of total testosterone.
Methods
6-month, randomized, double-blind, placebo-controlled four-arm clinical. 45 men (47.38
± 5.03 years) were randomized into 4 groups (G1: control + placebo; G2: control +
Eurycoma longifolia; G3: concurrent training + placebo; G4: concurrent training + Eurycoma longifolia). 22 received a 200 mg supplement of Eurycoma longifolia and 23 underwent the intervention with concurrent training, 3 times a week for 60
min at progressive intensity.
Outcomes
International Index of Erectile Function (IIEF-5), Aging Male Scale (AMS) and total
testosterone.
Results
Erectile function demonstrated improvements in both interventions; however, the most
significant results were obtained by men allocated to concurrent training + Eurycoma longifolia.
Clinical implications
A 200 mg supplement of Eurycoma longifolia and the practice of concurrent training for 6 months significantly improved the erectile
function of men with ADAM.
Strengths & limitations
The study's design stands out as a strength, in addition to the six-month intervention.
The main limitation is the study not having groups that used only Eurycoma longifolia and only concurrent training.
Conclusion
The combination of Eurycoma longifolia and concurrent training improved erectile function and increased total testosterone
levels in men with ADAM.
Keywords
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Article info
Publication history
Published online: December 09, 2020
Accepted:
December 7,
2020
Received in revised form:
November 13,
2020
Received:
August 29,
2020
Identification
Copyright
© 2020 Elsevier B.V. All rights reserved.
