Advertisement
Research Article| Volume 142, P68-72, December 2020

Fall-related mortality trends in Australia and the United Kingdom: Implications for research and practice

  • Harry Wu
    Affiliations
    Departments of Clinical Pharmacology and Aged Care, Royal North Shore Hospital, St Leonards, NSW, Australia

    Laboratory of Ageing and Pharmacology, Kolling Institute of Medical Research, St Leonards, NSW, Australia

    Faculty of Medicine and Health, University of Sydney, NSW, Australia
    Search for articles by this author
  • John Mach
    Affiliations
    Departments of Clinical Pharmacology and Aged Care, Royal North Shore Hospital, St Leonards, NSW, Australia

    Laboratory of Ageing and Pharmacology, Kolling Institute of Medical Research, St Leonards, NSW, Australia

    Faculty of Medicine and Health, University of Sydney, NSW, Australia
    Search for articles by this author
  • David G. Le Couteur
    Affiliations
    Faculty of Medicine and Health, University of Sydney, NSW, Australia

    Ageing and Alzheimer’s Institute (AAAI), Centre for Education and Research on Ageing (CERA) and ANZAC Research Institute, Concord Hospital, Concord, NSW, Australia

    Charles Perkins Centre, University of Sydney, NSW, Australia
    Search for articles by this author
  • Sarah N. Hilmer
    Correspondence
    Corresponding author at: Kolling Institute of Medical Research, Royal North Shore Hospital, St Leonards, NSW 2065, Australia.
    Affiliations
    Departments of Clinical Pharmacology and Aged Care, Royal North Shore Hospital, St Leonards, NSW, Australia

    Laboratory of Ageing and Pharmacology, Kolling Institute of Medical Research, St Leonards, NSW, Australia

    Faculty of Medicine and Health, University of Sydney, NSW, Australia
    Search for articles by this author

      Highlights

      • To our knowledge, this is the first study to examine long-term nationwide age- and sex-specific trends in falls mortality in more than one country.
      • Reported fall-related deaths increased from 2006 to 2016 in Australia and the UK. There were distinct age and sex differences in mortality trends.
      • Death rates from falls increased with age. People aged ≥ 95 years had the highest mortality rate from falls.
      • Fall-related mortality rates declined in younger people and increased in older people over the study period in both countries.
      • Mortality from falls was higher in men, but it increased at a faster rate in women.

      Abstract

      Objectives

      To characterise changes in nationwide fall-related mortality rates in Australia and the United Kingdom (UK) between 2006 and 2016 by age group and sex.

      Study design

      Trend analysis of falls mortality data from World Health Organization (WHO) Mortality Database for the Australian and UK population.

      Main outcome measures

      We assessed age-specific, sex-specific and age-adjusted mortality rates. Mortality trends were assessed via the annual percentage change (APC) using joinpoint regression.

      Results

      The annual average age-adjusted falls mortality rate was 38.63 per 1,000,000 population in Australia, and 34.12 per 1,000,000 population in the UK. From 2006 to 2016, age-adjusted mortality rate due to falls increased in Australia and the UK by an average annual rate of 3.77% (95% CI 2.91% to 4.64%; p<0.01) and 2.11% (95% CI 1.43% to 2.80%; p<0.01) respectively. Death rates from falls increased with age. People aged ≥95 years had the highest mortality rate from falls in Australia and the UK. Men had a higher annual average age-adjusted mortality rate from falls than women (1.6 times higher in Australia and 1.7 times higher in the UK). Women had a larger annual percentage increase in falls mortality rate compared to men over the study period.

      Conclusions

      There was a major increase in reported fall-related deaths in Australia and the UK between 2006 and 2016, especially in the very elderly. Men had a higher mortality rate from falls than women. Factors contributing to the apparent increases in fall-related mortality may include reduced cancer and cardiovascular mortality and better ascertainment of cause of death.

      Keywords

      To read this article in full you will need to make a payment

      Purchase one-time access:

      Academic & Personal: 24 hour online accessCorporate R&D Professionals: 24 hour online access
      One-time access price info
      • For academic or personal research use, select 'Academic and Personal'
      • For corporate R&D use, select 'Corporate R&D Professionals'

      Subscribe:

      Subscribe to Maturitas
      Already a print subscriber? Claim online access
      Already an online subscriber? Sign in
      Institutional Access: Sign in to ScienceDirect

      References

      1. World Health Organization. Falls. Available from URL: https://www.who.int/news-room/fact-sheets/detail/falls. Accessed 5 December 2019.

        • Moller J.
        Projected Costs of Fall Related Injury to Older Persons Due to Demographic Change in Australia: Report to the Commonwealth Department of Health and Ageing.
        New Directions in Health and Safety, Canberra2003
        • Scuffham P.
        • Chaplin S.
        • Legood R.
        Incidence and costs of unintentional falls in older people in the United Kingdom.
        J. Epidemiol. Community Health. 2003; 57: 740-744
        • Flicker L.
        • MacInnis R.J.
        • Stein M.S.
        • Scherer S.C.
        • Mead K.E.
        • Nowson C.A.
        • et al.
        Should older people in residential care receive vitamin D to prevent falls? Results of a randomized trial.
        J. Am. Geriatr. Soc. 2005; 53: 1881-1888
        • Gillespie L.D.
        • Robertson M.C.
        • Gillespie W.J.
        • Lamb S.E.
        • Gates S.
        • Cumming R.G.
        • et al.
        Interventions for preventing falls in older people living in the community.
        Cochrane Database Syst. Rev. 2009; Cd007146
        • Close J.
        • Ellis M.
        • Hooper R.
        • Glucksman E.
        • Jackson S.
        • Swift C.
        Prevention of falls in the elderly trial (PROFET): a randomised controlled trial.
        Lancet (London, England). 1999; 353: 93-97
        • Clemson L.
        • Cumming R.G.
        • Kendig H.
        • Swann M.
        • Heard R.
        • Taylor K.
        The effectiveness of a community-based program for reducing the incidence of falls in the elderly: a randomized trial.
        J. Am. Geriatr. Soc. 2004; 52: 1487-1494
        • Grigoryan K.V.
        • Javedan H.
        • Rudolph J.L.
        Orthogeriatric care models and outcomes in hip fracture patients: a systematic review and meta-analysis.
        J. Orthop. Trauma. 2014; 28: e49-55
        • Hartholt K.A.
        • Lee R.
        • Burns E.R.
        • van Beeck E.F.
        Mortality from falls among US adults aged 75 years or older, 2000-2016.
        Jama. 2019; 321: 2131-2133
        • Hartholt K.A.
        • van Beeck E.F.
        • van der Cammen T.J.M.
        Mortality from falls in dutch adults 80 years and older, 2000-2016.
        Jama. 2018; 319: 1380-1382
        • Padron-Monedero A.
        • Damian J.
        • Pilar Martin M.
        • Fernandez-Cuenca R.
        Mortality trends for accidental falls in older people in Spain, 2000-2015.
        BMC Geriatr. 2017; 17: 276
      2. Australian Bureau of Statistics. ABS.Stat. Australian Government. Available from URL: http://stat.data.abs.gov.au/. Accessed 5 December 2019.

      3. Population Estimates for the UK, England and Wales, Scotland and Northern Ireland: Mid-.
        Office for National Statistics, 2018 (Available from URL: https://www.ons.gov.uk/peoplepopulationandcommunity/populationandmigration/populationestimates/bulletins/annualmidyearpopulationestimates/mid2018. Accessed 5 December 2019)
        • Ahmad O.B.
        • Boschi-Pinto C.
        • Lopez A.D.
        • Murray C.J.
        • Lozano R.
        • Inoue M.
        Age Standardization of Rates: a New WHO Standard.
        World Health Organization, Geneva, Switzerland2001: 2001
        • O’Flaherty M.
        • Bishop J.
        • Redpath A.
        • McLaughlin T.
        • Murphy D.
        • Chalmers J.
        • et al.
        Coronary heart disease mortality among young adults in Scotland in relation to social inequalities: time trend study.
        BMJ. 2009; 339: b2613
        • Lopez-Campos J.L.
        • Ruiz-Ramos M.
        • Soriano J.B.
        Mortality trends in chronic obstructive pulmonary disease in Europe, 1994-2010: a joinpoint regression analysis.
        Lancet Respir. Med. 2014; 2: 54-62
        • Kim H.J.
        • Fay M.P.
        • Feuer E.J.
        • Midthune D.N.
        Permutation tests for joinpoint regression with applications to cancer rates.
        Stat. Med. 2000; 19: 335-351
        • Benvenuto L.J.
        • Krakoff L.R.
        Morbidity and mortality of orthostatic hypotension: implications for management of cardiovascular disease.
        Am. J. Hypertens. 2011; 24: 135-144
        • Dhalwani N.N.
        • Fahami R.
        • Sathanapally H.
        • Seidu S.
        • Davies M.J.
        • Khunti K.
        Association between polypharmacy and falls in older adults: a longitudinal study from England.
        BMJ Open. 2017; 7e016358
        • Gnjidic D.
        • Hilmer S.N.
        • Blyth F.M.
        • Naganathan V.
        • Cumming R.G.
        • Handelsman D.J.
        • et al.
        High-risk prescribing and incidence of frailty among older community-dwelling men.
        Clin. Pharmacol. Ther. 2012; 91: 521-528
        • Gale C.R.
        • Cooper C.
        • Sayer A.A.
        Prevalence of frailty and disability: findings from the English Longitudinal Study of Ageing.
        Age Ageing. 2015; 44: 162-165
        • Fairhall N.
        • Sherrington C.
        • Lord S.R.
        • Kurrle S.E.
        • Langron C.
        • Lockwood K.
        • et al.
        Effect of a multifactorial, interdisciplinary intervention on risk factors for falls and fall rate in frail older people: a randomised controlled trial.
        Age Ageing. 2013; 43: 616-622
        • Faes M.C.
        • Reelick M.F.
        • Melis R.J.
        • Borm G.F.
        • Esselink R.A.
        • Rikkert M.G.
        Multifactorial fall prevention for pairs of frail community-dwelling older fallers and their informal caregivers: a dead end for complex interventions in the frailest fallers.
        J. Am. Med. Dir. Assoc. 2011; 12: 451-458
        • Piskovatska V.
        • Stefanyshyn N.
        • Storey K.B.
        • Vaiserman A.M.
        • Lushchak O.
        Metformin as a geroprotector: experimental and clinical evidence.
        Biogerontology. 2019; 20: 33-48
        • Ensrud K.E.
        • Ewing S.K.
        • Taylor B.C.
        • Fink H.A.
        • Stone K.L.
        • Cauley J.A.
        • et al.
        Frailty and risk of falls, fracture, and mortality in older women: the study of osteoporotic fractures.
        J. Gerontol. A Biol. Sci. Med. Sci. 2007; 62: 744-751
        • Meschial W.C.
        • Soares D.F.
        • de Oliveira N.L.
        • Nespollo A.M.
        • da Silva W.A.
        • Santil F.L.
        Elderly victims of falls seen by prehospital care: gender differences.
        Rev. Bras. Epidemiol. 2014; 17: 3-16