Highlights
- •The prevalence of osteoporosis and low muscle mass was 8.9 % and 9.9 %, respectively.
- •Low muscle mass was significantly associated with osteoporosis in both men and women.
- •The significant association between low muscle mass and osteoporosis remained in all age groups except for men 50–64 years.
Abstract
Objectives
To assess the association between low muscle mass and osteoporosis in the Korean general
population.
Methods
We analyzed 14,429 participants (6,261 men and 8,168 women) from the 2009–2011 Korean
National Health and Nutrition Examination Survey (KNHANES) aged 20 years or more.
Main outcome measure
The association of low muscle mass with osteoporosis was investigated using multivariate
logistic regression models that included age, marital status, residence, current smoking,
monthly drinking, physical activities, strength exercise, comorbidity, and the use
of dietary supplements, and in women postmenopausal status and experience of pregnancy.
Results
After adjusting for covariates, low muscle mass was significantly associated with
osteoporosis in the lumbar spine and femoral neck in both men (lumbar spine: OR 1.73,
95 % CI 1.08–2.76; femoral neck: OR 3.39, 95 % CI 1.69–6.80) and women (lumbar spine:
OR 1.52, 95 % CI 1.17–1.97; femoral neck: OR 2.09, 95 % CI 1.56–2.80). Also, the association
between low muscle mass and osteoporosis was significant in men and women in every
age group except for men aged 50–64 years.
Conclusion
Low muscle mass was significantly associated with osteoporosis in both men and women
for all age groups, except for men aged 50–64 years.
Keywords
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Article info
Publication history
Published online: January 07, 2020
Accepted:
January 7,
2020
Received in revised form:
December 9,
2019
Received:
October 16,
2019
Identification
Copyright
© 2020 Elsevier B.V. All rights reserved.
