Highlights
- •Even when aware of the relevance of deprescribing for their clinical activity, Italian physicians find deprescribing difficult. .
- •Professionals are willing to challenge themselves and the barriers to deprescribing.
- •Reviewing prescriptions regularly and enhancing collaboration with colleagues and patients are suitable strategies.
Abstract
Background
Even though increasing attention is given to deprescribing owing to the risks related
to polypharmacy in older adults, deprescribing is not yet part of clinical culture.
Methods
We conducted three focus groups with 25 internists, geriatricians and general practitioners
to explore the factors influencing the implementation of deprescribing in the Italian
context, and more specifically: i. to investigate the barriers to deprescribing; ii.
to define strategies and actions to address these barriers; and iii. to identify skills
and tools that may assist in implementing deprescribing in clinical practice. Thematic
analysis was used.
Results
Six themes were identified: Good reasons for deprescribing, Difficulties and doubts
about deprescribing, System factors affecting polypharmacy and deprescribing, Perspectives
on how to practically approach polypharmacy, Need for effective communication with
patients and caregivers, Taking responsibility and starting action.
Participants reported a willingness to challenge themselves by addressing the barriers
to deprescribing through regular review of prescriptions and collaboration with colleagues
and patients.
Conclusions
Italian internists, geriatricians and general practitioners reported many system-level
barriers to deprescribing as well as some doubts about its necessity. Strategies to
address the barriers to deprescribing include regular medication review and enhancing
collaboration with colleagues and patients. Additionally, participants were willing
to challenge themselves and use uncertainty as an impetus for deprescribing.
Keywords
To read this article in full you will need to make a payment
Purchase one-time access:
Academic & Personal: 24 hour online accessCorporate R&D Professionals: 24 hour online accessOne-time access price info
- For academic or personal research use, select 'Academic and Personal'
- For corporate R&D use, select 'Corporate R&D Professionals'
Subscribe:
Subscribe to MaturitasAlready a print subscriber? Claim online access
Already an online subscriber? Sign in
Register: Create an account
Institutional Access: Sign in to ScienceDirect
References
- Too much medicine in older people? Deprescribing through shared decision making.BMJ. 2016; 353: i2893https://doi.org/10.1136/bmj.i2893
- How can we effectively engage physicians in the deprescribing process?.Am. J. Med. Qual. 2017; 32: 581-582https://doi.org/10.1177/1062860617704899
- Medication withdrawal trials in people aged 65 years and older: a systematic review.Drugs Aging. 2008; 25: 1021-1031https://doi.org/10.2165/0002512-200825120-00004
- The feasibility and effect of deprescribing in older adults on mortality and health: a systematic review and meta-analysis.Br. J. Clin. Pharmacol. 2016; 82: 583-623https://doi.org/10.1111/bcp.12975
- Poly-de-prescribing to treat polypharmacy: efficacy and safety.Ther. Adv. Drug Saf. 2018; 9: 25-43https://doi.org/10.1177/2042098617736192
- A narrative review of the safety concerns of deprescribing in older adults and strategies to mitigate potential harms.Expert Opin. Drug Saf. 2018; 17: 39-49https://doi.org/10.1080/14740338.2018.1397625
- Withdrawal versus continuation of chronic antipsychotic drugs for behavioural and psychological symptoms in older people with dementia.Cochrane Database Syst. Rev. 2013; (CD007726)https://doi.org/10.1002/14651858.CD007726.pub2
- Deprescribing: a narrative review of the evidence and practical recommendations for recognizing opportunities and taking action.Eur. J. Intern. Med. 2017; 38: 3-11https://doi.org/10.1016/j.ejim.2016.12.021
- Deprescribing medications for older adults in the primary care context: a mixed studies review.Health Sci. Rep. 2018; 1 (e45)https://doi.org/10.1002/hsr2.45
- Factors influencing deprescribing for residents in Advanced Care Facilities: insights from General Practitioners in Australia and Sweden.BMC Fam. Pract. 2016; 17: 152https://doi.org/10.1186/s12875-016-0551-7
- Reducing polypharmacy from the perspectives of General Practitioners and older patients: a synthesis of qualitative studies.Drugs Aging. 2016; 33: 249-266https://doi.org/10.1007/s40266-016-0354-5
- Prescriber barriers and enablers to minimising potentially inappropriate medications in adults: a systematic review and thematic synthesis.BMJ Open. 2014; 4 (e006544)https://doi.org/10.1136/bmjopen-2014-006544
- Challenges and enablers of deprescribing: a general practitioner perspective.PLoS One. 2016; 11 (e0151066)https://doi.org/10.1371/journal.pone.0151066
- Clinical practice guidelines for older people with multimorbidity and life-limiting illness: what are the implications for deprescribing?.Ther. Adv. Drug Saf. 2018; 9: 619-630https://doi.org/10.1177/2042098618795770
- Prescribing and deprescribing antihypertensive medication in older people by Dutch general practitioners: a qualitative study.BMJ Open. 2018; 8 (e020871)https://doi.org/10.1136/bmjopen-2017-020871
- Negotiating “unmeasurable harm and benefit”: perspectives of general practitioners and consultant pharmacists on deprescribing in the primary care setting.Qual. Health Res. 2017; 27: 1936-1947https://doi.org/10.1177/1049732316687732
- Swimming against the tyde. Primary care physicians’ views on deprescribing in everyday practice.Ann. Fam. Med. 2017; 15: 341-346https://doi.org/10.1370/afm.2094
- Organising medication discontinuation: a qualitative study exploring the views of general practitioners toward discontinuing statins.BMC Health Serv. Res. 2016; 16: 226https://doi.org/10.1186/s12913-016-1495-2
- The ethics of deprescribing in older adults.J. Bioeth. Inquiry. 2016; 13: 581-590https://doi.org/10.1007/s11673-016-9736-y
- How confident are physicians in deprescribing for the elderly and what barriers prevent deprescribing?.J. Clin. Pharm. Ther. 2018; 43: 550-555https://doi.org/10.1111/jcpt.12688
- Polypharmacy, length of hospital stay, and in-hospital mortality among elderly patients in internal medicine wards. The REPOSI study.Eur. J. Clin. Pharmacol. 2011; 67: 5017-5519https://doi.org/10.1016/j.ejim.2011.08.029
- Consolidated criteria for reporting qualitative research (COREQ): a 32-item checklist for interviews and focus groups.Int. J. Qual. Health Care. 2007; 19: 349-357https://doi.org/10.1093/intqhc/mzm042
- Constructing Grounded Theory: A Practical Guide Through Qualitatitve Analysis.SAGE, London2006
- Using thematic analysis in psychology.Qualitat. Res. Psychol. 2006; 3: 77-101
- Outing the researcher: the provenance, process and practice of reflexivity.Qual. Health Res. 2002; 12: 531-545
- Barricades and brickwalls--a qualitative study exploring perceptions of medication use and deprescribing in long-term care.BMC Geriatr. 2016; 16: 15https://doi.org/10.1186/s12877-016-0181-x
- Attitudes towards polypharmacy and medication withdrawal among older inpatients in Italy.Int. J. Clin. Pharm. 2016; 38: 454-461https://doi.org/10.1007/s11096-016-0279-4
- Assessment of attitudes toward deprescribing in older medicare beneficiaries in the United States.JAMA Intern. Med. 2018; 178: 1673-1680https://doi.org/10.1001/jamainternmed.2018.4720
- GPs’ and pharmacists’ experiences of managing multimorbidity: a ’Pandora’s box’.Br. J. Gen. Pract. 2010; 60: 285-294https://doi.org/10.3399/bjgp10X514756
- GPs’ perceptions of multiple-medicine use in older patients.J. Eval. Clin. Pract. 2010; 16: 69-75https://doi.org/10.1111/j.1365-2753.2008.01116.x
Article info
Publication history
Published online: January 24, 2020
Accepted:
January 18,
2020
Received in revised form:
January 7,
2020
Received:
August 28,
2019
Identification
Copyright
© 2020 Elsevier B.V. All rights reserved.