Menopausal transition is a period characterized by psychic, somatic and changes in
the reproductive capacity of a woman. It occurs as a result of quenching of the ovarian
function, and refers to periods with different meanings: perimenopause, menopause
and postmenopausal. The level of lipoprotein in girls and boys in puberty is similar.
The gender difference in HDL cholesterol occurs during puberty and women have an average
10 mg / dL higher HDL cholesterol level than men throughout their lifetime. According
to recent studies, it affects HDL cholesterol and reduced triglyceride levels, and
a longer reproductive period is also associated with increased body weight, and unlike
years of menstruation, it is characterized by a reduced level of HDL and all other
cholesterol. The aim of the study was to determine the relationship between menarche
and reproductive age with lipid and hormonal profiles in women in perimenopause and
postmenopausal women. This prospective, comparative survey was carried out in the
period from November 2014 to December 2015 and included a total of 150 respondents
divided into three groups and a life span of 40–55 years. Based on the obtained regression
coefficients and the corresponding P values, we can not conclude that there is a significant
relationship between menarche and lipid profile in subjects in premenopausal, perimenopause
and postmenopausal, and we can not confirm that there is a significant relationship
between reproductive age and lipid profile. Lifetime is an important independent predictor
for LDL and total cholesterol in women, but it is not as influential as a body constitution
and lifestyle affect the level of HDL, LDL, and triglycerides in women.
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Publication history
Published online: August 06, 2019
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© 2019 Published by Elsevier Inc.