Highlights
- •Transcutaneous tibial nerve stimulation is indicated as the first-line treatment for older women with an overactive bladder.
- •Transcutaneous tibial nerve stimulation is safe and tolerable for older women.
- •Sensory and motor thresholds of transcutaneous tibial nerve stimulation show the same effectiveness for overactive bladder.
Abstract
Objectives:To compare the effectiveness of transcutaneous tibial nerve stimulation
(TTNS) at two different current amplitude thresholds (sensory and motor) in terms
of urinary habit, symptoms and the degree of discomfort of overactive bladder (OAB)
in older women.
Study design
This is a randomized, controlled, 3-arm blinded trial. One hundred and one patients
attending secondary care with OAB were randomized into one of three groups: group
1, TTNS sensitivity threshold (n = 39); group 2, TTNS motor threshold (n = 33); and
control group 3 (n = 29).
Main outcome measures
Participants allocated to groups 1 and 2 had 8 sessions of TTNS for 30 min, twice
a week. Group 3 received no intervention. The results measured were the symptoms of
overactive bladder (ICIQ-OAB, overall score), bother scales (to indicate the impact
of individual symptoms for the patient) and urinary habit (3-day bladder diary). A
blind assessor measured outcomes at baseline and 5 weeks after randomization.
Results
After five weeks, a statistically significant difference between group 3 (control)
and group 1 (TTNS sensitivity threshold) and group 2 (TTNS motor threshold) was observed
in the intergroup analysis, but no difference in the outcomes analyzed was detected
between the two groups receiving intervention (groups 1 and 2).
Conclusion
TTNS is effective in the treatment of OAB in older women, with no difference between
the sensitivity and motor thresholds.
Clinical trial registration number
Registro Brasileiros de Ensaios Clínicos (RBR-39DZ5V)
Keywords
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Article info
Publication history
Published online: February 24, 2020
Accepted:
February 23,
2020
Received in revised form:
October 1,
2019
Received:
July 10,
2019
Identification
Copyright
© 2020 Elsevier B.V. All rights reserved.
