Research Article| Volume 129, P23-29, November 2019

Group cognitive behavioural therapy of physical and psychological menopausal symptoms of Chinese women, delivered via Internet and mobile phone versus face to face: A protocol for a randomized non-inferiority trial


      • This article describes the protocol for a study of interventions to alleviate menopausal syndrome and its related mood swings.
      • The protocol sets out the rationale and methods for a trial of group cognitive behavioural therapy in menopausal women.
      • The aim is to evaluate the efficacy of group therapy delivered via the Internet or mobile phone and of face-to-face group treatment.



      Menopause syndrome generally includes psychological problems. Group treatment delivered via the Internet and mobile phone (imGT) may improve women’s physiological and psychological conditions.


      To investigate the efficacy of group cognitive behavioural therapy of menopause-related mood swings and quality of life, delivered face to face or via the Internet and mobile phone.


      This protocol is for a randomized controlled clinical trial with a sample of 140 menopausal women divided into 2 groups: imGT and face-to-face group treatment (ffGT). The primary outcome will be the improvement in the menopausal symptoms of the two groups, as assessed by the Greene Climacteric Scale. The secondary outcomes will be: quality of life, assessed by the Short Form 36 Health Survey Questionnaire; insomnia, assessed by the Pittsburgh Sleep Quality Inventory; anxiety, assessed by the Hamilton Anxiety Rating Scale; and therapeutic alliance, assessed by the Working Alliance Inventory-Short Revised and Client Sat­is­fac­tion Qes­tion­naire-8. imGT will be performed once a week for 1.5 h for 10 weeks with a daily ‘Punched-in’ on the WeChat app; ffGT will be performed once a week for 1.5 h for 10 weeks. All outcomes will be assessed at baseline, at a post-intervention evaluation (week 10), and at a follow-up evaluation (week 22).


      This study will be the first clinical trial to examine the effects of imGT on menopausal women in China. If imGT is found to be non-inferior to ffGT, it will facilitate access to menopausal health services.


      imGT (group treatment delivered via the Internet and mobile phone), ffGT (face-to-face group treatment), GT (group treatment), CBT (cognitive behavioural therapy), QOL (quality of life)


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