Research Article| Volume 128, P36-42, October 2019

Association between physical inactivity and health-related quality of life in adults with coronary heart disease

  • Reginald Wardoku
    Division of Epidemiology and Community Health, University of Minnesota, United States
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  • Cindy Blair
    Department of Internal Medicine, University of New Mexico, United States

    University of New Mexico Comprehensive Cancer Center, United States
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  • Ryan Demmer
    Division of Epidemiology and Community Health, University of Minnesota, United States

    Department of Epidemiology, Mailman School of Public Health, Columbia University, New York, NY, United States
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  • Anna Prizment
    Corresponding author at: Division of Epidemiology & Community Health, University of Minnesota School of Public Health, 1300 S 2nd St, Suite 300, Minneapolis, MN, 55454, United States.
    Division of Epidemiology and Community Health, University of Minnesota, United States

    Masonic Cancer Center, University of Minnesota, United States
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      • Health-related quality of life (HRQoL) is an important health indicator in adults with coronary heart disease (CHD).
      • Physical inactivity was associated with both poor physical and mental HRQol in CHD patients.
      • The association is stronger for physical than mental HRQoL.



      Health-related quality of life (HRQoL) provides an accurate measure of the health status of patients with coronary heart disease (CHD). However, few studies have examined the relationship between physical inactivity and HRQoL in CHD survivors. We evaluated this association in a cross-sectional study of 21,936 CHD participants in the 2015 Behavioral Risk Factor Surveillance System.


      CHD diagnosis, HRQoL and physical activity were self-reported. Physical activity (PA) was categorized (1) based on intensity, into no PA, light to moderate PA and vigorous PA; and (2) based on duration and frequency, into no PA, insufficiently active and active. HRQoL was assessed by the CDC HRQoL questionnaire. Participants with 14+ physical or mental unhealthy days in a 30-day window were grouped into poor physical or mental HRQoL. We estimated the odd ratios (AOR) and 95% confidence intervals (CI) of poor HRQoL associated with PA after adjusting for age, sex, education, income level, social support, smoking status, ethnicity/race, BMI, chronic conditions, and CHD groups.


      Compared with vigorous PA, adults with no PA had higher odds (95% CI) of poor physical HRQoL [1.82 (1.58, 2.10)] and poor mental HRQoL [1.28 (1.05, 1.55)]. When compared with active adults, AOR (95% CI) for adults with no PA were 1.80 (1.55, 2.01) and 1.17 (0.97, 1.42) for poor physical and mental HRQoL, respectively.


      We found an association between physical inactivity and poor physical and mental HRQoL among CHD survivors. There is a need for longitudinal studies to determine the temporality of this association.


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