A clinical prescription for heart health in midlife women

  • Chrisandra Shufelt
    Corresponding author at: Barbra Streisand Women’s Heart Center, Cedars-Sinai Smidt Heart Institute, Cedars-Sinai Medical Center, 8631 W. Third Street, Suite 740 East, Los Angeles, CA 90048, USA.
    Barbra Streisand Women’s Heart Center, Cedars-Sinai Smidt Heart Institute, Cedars-Sinai Medical Center, Los Angeles, CA, USA
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  • Erika Dutra
    Barbra Streisand Women’s Heart Center, Cedars-Sinai Smidt Heart Institute, Cedars-Sinai Medical Center, Los Angeles, CA, USA
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  • Tina Torbati
    Barbra Streisand Women’s Heart Center, Cedars-Sinai Smidt Heart Institute, Cedars-Sinai Medical Center, Los Angeles, CA, USA
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  • Tina Ramineni
    Barbra Streisand Women’s Heart Center, Cedars-Sinai Smidt Heart Institute, Cedars-Sinai Medical Center, Los Angeles, CA, USA
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      • Cardiovascular disease is the leading cause of death in women throughout the United States and Europe.
      • Midlife provides an opportunity for healthcare providers to provide education and counseling about healthy lifestyle changes.
      • Novel CVD risk factors include adverse pregnancy outcomes, autoimmune diseases, depression, and cancer treatments.


      Cardiovascular disease is the leading cause of death in women throughout the United States and Europe. Despite efforts to raise awareness, the sex-specific risk factors are still poorly recognized in both regions, and many women do not identify cardiovascular disease as a primary threat. During midlife, the incidence of cardiovascular disease increases dramatically, and this unique time gives an opportunity to identify both traditional cardiovascular risk factors as well as emerging risk factors unique to women. This review will focus on the current guidelines for cardiovascular risk assessment in Europe and the United States, traditional and emerging cardiovascular risk factors, and preventive lifestyle recommendations for midlife women.


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