Background: Carotid atherosclerosis remains an important etiological factor of ischemic stroke.
Sex differences have been observed in carotid plaque composition and in stroke incidence.
Sex steroids have been suggested to count for these sex differences, but the evidence
in humans is limited. Therefore, we aimed to study the associations of endogenous
estradiol and testosterone with carotid plaque composition in middle-aged and elderly
men and postmenopausal women with carotid atherosclerosis, as well as with risk of
stroke in this population.
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© 2017 Published by Elsevier Inc.