Advertisement

Bespoke or one size fits all—Vitamin D fortification, targeted supplementation in risk groups or individual measurement?

  • Bo Abrahamsen
    Correspondence
    *Correspondence address: Department of Medicine, Holbæk Hospital, Holbæk, Denmark.
    Affiliations
    Department of Medicine, Holbæk Hospital, Holbæk, Denmark

    Odense Patient Data Explorative Network, Institute of Clinical Research, University of Southern Denmark, Odense, Denmark
    Search for articles by this author
      Vitamin D insufficiency is prevalent in Northern Europe, particularly in winter and spring given the low sunlight UVB intensity in winter months which precludes vitamin D production even if the skin is exposed. Though association studies have linked, in many cases controversially, low vitamin D status to an increased risk of outcomes, the least controversial effect of vitamin D is on the skeleton where calcium and vitamin D supplementation in combination modestly reduce the risk of fractures in the elderly population. Severe nutritional rickets or osteomalacia are unusual but by no means eradicated in Western Europe.
      To read this article in full you will need to make a payment

      Purchase one-time access:

      Academic & Personal: 24 hour online accessCorporate R&D Professionals: 24 hour online access
      One-time access price info
      • For academic or personal research use, select 'Academic and Personal'
      • For corporate R&D use, select 'Corporate R&D Professionals'

      Subscribe:

      Subscribe to Maturitas
      Already a print subscriber? Claim online access
      Already an online subscriber? Sign in
      Institutional Access: Sign in to ScienceDirect

      References

        • Spiro A.
        • Buttriss J.L.
        Vitamin D: an overview of vitamin D status and intake in Europe.
        Nutr. Bull. 2014; 39: 322-350
        • Reid I.R.
        • Horne A.M.
        • Mihov B.
        • Gamble G.D.
        • Fenwick S.
        • Camargo Jr., C.A.
        • Stewart A.W.
        • Scragg R.
        RCT of monthly high-dose Vitamin D on bne density in community-dwelling older adults: trial-based evidence for defining Vitamin D deficiency (abstract).
        Calcif. Tissue Int. 2017; 100 (p. S21)
        • Khaw K.-T.
        • Stewart A.W.
        • Med D.W.
        • Mbchb C.M.M.L.
        • Les P.
        • Mbchb T.
        • Carlos P.
        • Robert Jr, A.C.P.
        • Mbbs S.
        Articles effect of monthly high-dose vitamin D supplementation on falls and non-vertebral fractures: secondary and post-hoc outcomes from the randomised, double-blind.
        Lancet Diabetes Endocrinol. 2017; 8587: 1-10
        • Bolland M.J.
        • Grey A.
        • Reid I.R.
        Differences in overlapping meta-analyses of Vitamin D supplements and falls.
        J. Clin. Endocrinol. Metab. 2014; 99: 4265-4272
        • Hill T.R.
        • Aspray T.J.
        Vitamin D prescribing in older people in the UK depends on postcode.
        Maturitas. 2017; 99: 109-113