Advertisement
Research Article| Volume 92, P41-48, October 2016

Reducing depression during the menopausal transition with health coaching: Results from the healthy menopausal transition randomised controlled trial

  • Osvaldo P. Almeida
    Correspondence
    Corresponding author at: WA Centre for Health & Ageing (M573), University of Western Australia, 35 Stirling Highway, Crawley, WA 6009, Australia.
    Affiliations
    Western Australian Centre for Health & Ageing (M573), Centre for Medical Research of the Perkins Institute for Medical Research, University of Western Australia, 35 Stirling Highway, Crawley, WA 6009, Australia

    School of Psychiatry & Clinical Neurosciences, University of Western Australia, Australia

    Department of Psychiatry, Royal Perth Hospital, Australia
    Search for articles by this author
  • Kylie Marsh
    Affiliations
    Western Australian Centre for Health & Ageing (M573), Centre for Medical Research of the Perkins Institute for Medical Research, University of Western Australia, 35 Stirling Highway, Crawley, WA 6009, Australia

    School of Psychiatry & Clinical Neurosciences, University of Western Australia, Australia
    Search for articles by this author
  • Karen Murray
    Affiliations
    Western Australian Centre for Health & Ageing (M573), Centre for Medical Research of the Perkins Institute for Medical Research, University of Western Australia, 35 Stirling Highway, Crawley, WA 6009, Australia

    School of Psychiatry & Clinical Neurosciences, University of Western Australia, Australia
    Search for articles by this author
  • Martha Hickey
    Affiliations
    Department of Obstetrics & Gynaecology, University of Melbourne and Royal Women’s Hospital, Parkville, VIC 3052, Australia
    Search for articles by this author
  • Moira Sim
    Affiliations
    School of Medical Sciences, Edith Cowan University, Joondalup, WA 6027, Australia
    Search for articles by this author
  • Andrew Ford
    Affiliations
    Western Australian Centre for Health & Ageing (M573), Centre for Medical Research of the Perkins Institute for Medical Research, University of Western Australia, 35 Stirling Highway, Crawley, WA 6009, Australia

    School of Psychiatry & Clinical Neurosciences, University of Western Australia, Australia

    Department of Psychiatry, Royal Perth Hospital, Australia
    Search for articles by this author
  • Leon Flicker
    Affiliations
    Western Australian Centre for Health & Ageing (M573), Centre for Medical Research of the Perkins Institute for Medical Research, University of Western Australia, 35 Stirling Highway, Crawley, WA 6009, Australia

    School of Medicine and Pharmacology, University of Western Australia, Australia

    Department of Geriatric Medicine, Royal Perth Hospital, Australia
    Search for articles by this author

      Highlights

      • The menopausal transition is considered a time of increased vulnerability to depression.
      • We used health coaching to address risk factors associated with depression during the menopausal transition.
      • Compared with usual care, health coaching led to a greater decline in the severity of depressive symptoms over 12 months.
      • Women with sub-threshold symptoms of depression at baseline benefited most from the intervention.
      • Health coaching could play a useful role in decreasing mental health disturbances associated with the menopausal transition.

      Abstract

      Objective

      To determine if health coaching (HC) decreases the incidence of depression, reduces the severity of symptoms, and increases quality of life during the menopausal transition (MT).

      Research design and methods

      Parallel, single-blinded, randomised controlled trial of 6 sessions of phone-delivered HC compared with usual care. Participants were 351 community-dwelling women free of major depression going through the MT, of whom 180 were assigned the intervention and 171 usual care. The primary outcome of interest was the incidence of clinically significant depressive symptoms over 52 weeks. Other study measures included the Hospital Anxiety and Depression Scale, quality of life (SF-12), the Menopause Rating Scale (MRS), diet, body mass index, alcohol use, smoking and physical activity. We considered that women with Patient Health Questionnaire (PHQ-9) scores between 5 and 14 (inclusive) had sub-threshold depressive symptoms.

      Results

      Nine women developed clinically significant symptoms of depression during the study—2 had been assigned HC (odds ratio, OR = 0.26, 95%CI = 0.05, 1.29; p = 0.099). Intention-to-treat showed that, compared with usual care, the intervention led to a greater decline in depressive scores, most markedly for participants with sub-threshold depressive symptoms. Similar, but less pronounced, benefits were noticed for anxiety scores and the mental component summary of the SF-12. The intervention led to a decline in MRS scores by week 26 and subtle improvements in body mass, consumption of vegetables and smoking.

      Conclusions

      HC addressing relevant risk factors for depression during the MT improves mental health measures. Our findings indicate that women with sub-threshold depressive symptoms may benefit the most from such interventions, and suggest that HC could play a useful role in minimizing mental health disturbance for women going through the MT.

      Keywords

      To read this article in full you will need to make a payment

      Purchase one-time access:

      Academic & Personal: 24 hour online accessCorporate R&D Professionals: 24 hour online access
      One-time access price info
      • For academic or personal research use, select 'Academic and Personal'
      • For corporate R&D use, select 'Corporate R&D Professionals'

      Subscribe:

      Subscribe to Maturitas
      Already a print subscriber? Claim online access
      Already an online subscriber? Sign in
      Institutional Access: Sign in to ScienceDirect

      References

        • Soares C.N.
        Depression during the menopausal transition: window of vulnerability or continuum of risk.
        Menopause. 2008; 15: 207-209
        • Freeman E.W.
        Associations of depression with the transition to menopause.
        Menopause. 2010; 17: 823-827
        • Cohen L.S.
        • Soares C.N.
        • Vitonis A.F.
        • Otto M.W.
        • Harlow B.L.
        Risk for new onset of depression during the menopausal transition: the Harvard study of moods and cycles.
        Arch. Gen. Psychiatry. 2006; 63: 385-390
        • Schmidt P.J.
        • Haq N.
        • Rubinow D.R.
        A longitudinal evaluation of the relationship between reproductive status and mood in perimenopausal women.
        Am. J. Psychiatry. 2004; 161: 2238-2244
        • Schmidt P.J.
        Mood, depression, and reproductive hormones in the menopausal transition.
        Am. J. Med. 2005; 118: 54-58
        • Freeman E.W.
        • Sammel M.D.
        • Lin H.
        • Gracia C.R.
        • Pien G.W.
        • Nelson D.B.
        • et al.
        Symptoms associated with menopausal transition and reproductive hormones in midlife women.
        Obstet. Gynecol. 2007; 110: 230-240
        • Freeman E.W.
        • Sammel M.D.
        • Lin H.
        • Nelson D.B.
        Associations of hormones and menopausal status with depressed mood in women with no history of depression.
        Arch. Gen. Psychiatry. 2006; 63: 375-382
        • Gyllstrom M.E.
        • Schreiner P.J.
        • Harlow B.L.
        Perimenopause and depression: strength of association, causal mechanisms and treatment recommendations.
        Best Pract. Res. Clin. Obstet. Gynaecol. 2007; 21: 275-292
        • Woods N.F.
        • Smith-DiJulio K.
        • Percival D.B.
        • Tao E.Y.
        • Mariella A.
        • Mitchell S.
        Depressed mood during the menopausal transition and early postmenopause: observations from the Seattle midlife women’s health study.
        Menopause. 2008; 15: 223-232
        • Almeida O.P.
        • Marsh K.
        • Flicker L.
        • Hickey M.
        • Sim M.
        • Ford A.
        Depressive symptoms in midlife: the role of reproductive stage.
        Menopause. 2016; 23: 669-675
        • Brown W.J.
        • Ford J.H.
        • Burton N.W.
        • Marshall A.L.
        • Dobson A.J.
        Prospective study of physical activity and depressive symptoms in middle-aged women.
        Am. J. Prev. Med. 2005; 29: 265-272
        • Palmer S.
        • Tubbs I.
        • Whybrow A.
        Health coaching to facilitate the promotion of healthy behaviour and achievement of health-related goals.
        Int. J. Health Promot. Educ. 2003; 41: 91-93
        • Vale M.J.
        • Jelinek M.V.
        • Best J.D.
        • Dart A.M.
        • Grigg L.E.
        • Hare D.L.
        • et al.
        Coaching patients on achieving cardiovascular health (COACH): a multicenter randomized trial in patients with coronary heart disease.
        Arch. Intern. Med. 2003; 163: 2775-2783
        • Wolever R.Q.
        • Dreusicke M.
        • Fikkan J.
        • Hawkins T.V.
        • Yeung S.
        • Wakefield J.
        • et al.
        Integrative health coaching for patients with type 2 diabetes: a randomized clinical trial.
        Diabetes Educ. 2010; 36: 629-639
        • Almeida O.P.
        • Marsh K.
        • Flicker L.
        • Hickey M.
        • Ford A.
        • Sim M.
        Reducing depression during the menopausal transition: study protocol for a randomised controlled trial.
        Trials. 2014; 15: 312
        • Harlow S.D.
        • Gass M.
        • Hall J.E.
        • Lobo R.
        • Maki P.
        • Rebar R.W.
        • et al.
        Executive summary of the stages of reproductive aging workshop +10: addressing the unfinished agenda of staging reproductive aging.
        Menopause. 2012; 19: 387-395
        • Kroenke K.
        • Spitzer R.L.
        • Williams J.B.
        The PHQ-9: validity of a brief depression severity measure.
        J. Gen. Intern. Med. 2001; 16: 606-613
        • Sheehan D.V.
        • Lecrubier Y.
        • Sheehan K.H.
        • Amorim P.
        • Janavs J.
        • Weiller E.
        • et al.
        The mini-international neuropsychiatric Interview (M.I.N.I.): the development and validation of a structured diagnostic psychiatric interview for DSM-IV and ICD-10.
        J. Clin. Psychiatry. 1998; 59 (quiz 4–57): 22-33
        • Zigmond A.S.
        • Snaith R.P.
        The hospital anxiety and depression scale.
        Acta Psychiatr. Scand. 1983; 67: 361-370
      1. Australian Bureau of Statistics. National Health Survey: SF-36 Population Norms, Australia. ABS. 4399.0 4399.0.1995.

        • Heinemann K.
        • Ruebig A.
        • Potthoff P.
        • Schneider H.P.
        • Strelow F.
        • Heinemann L.A.
        • et al.
        The menopause rating scale (MRS) scale: a methodological review.
        Health Qual. Life Outcomes. 2004; 2: 45
        • Saunders J.B.
        • Aasland O.G.
        • Babor T.F.
        • de la Fuente J.R.
        • Grant M.
        Development of the alcohol use disorders identification test (AUDIT): WHO collaborative project on early detection of persons with harmful alcohol consumption–II.
        Addiction. 1993; 88: 791-804
      2. National Health and Medical Research Council. Australian Dietary Guidelines. Canberra: National Health and Medical Research Council. 2013.

        • Hollingworth S.A.
        • Burgess P.M.
        • Whiteford H.A.
        Affective and anxiety disorders: prevalence, treatment and antidepressant medication use.
        Aust. N. Z. J. Psychiatry. 2010; 44: 513-519
        • Lyness J.M.
        • Heo M.
        • Datto C.J.
        • Ten Have T.R.
        • Katz I.R.
        • Drayer R.
        • et al.
        Outcomes of minor and subsyndromal depression among elderly patients in primary care settings.
        Ann. Intern. Med. 2006; 144: 496-504
        • Kroenke K.
        • Spitzer R.L.
        The PHQ-9: a new depression diagnostic and severity measure.
        Psychiatr. Ann. 2002; 32: 509-521
        • McKinlay S.M.
        The normal menopause transition: an overview.
        Maturitas. 1996; 23: 137-145
        • Palmer S.
        • Tubbs I.
        • Whybrow A.
        Health coaching to facilitate the promotion of healthy behaviour and achievement of health-related goals.
        Int. J. Health Promot. Educ. 2003; 41: 91-93
        • Appel L.J.
        • Clark J.M.
        • Yeh H.C.
        • Wang N.Y.
        • Coughlin J.W.
        • Daumit G.
        • et al.
        Comparative effectiveness of weight-loss interventions in clinical practice.
        N. Engl. J. Med. 2011; 365: 1959-1968
        • Katon W.J.
        • Lin E.H.
        • Von Korff M.
        • Ciechanowski P.
        • Ludman E.J.
        • Young B.
        • et al.
        Collaborative care for patients with depression and chronic illnesses.
        N. Engl. J. Med. 2010; 363: 2611-2620
        • Almeida O.P.
        • Alfonso H.
        • Pirkis J.
        • Kerse N.
        • Sim M.
        • Flicker L.
        • et al.
        A practical approach to assess depression risk and to guide risk reduction strategies in later life.
        Int. Psychogeriatr. 2011; 23: 280-291
        • Almeida O.P.
        • Hankey G.J.
        • Yeap B.B.
        • Golledge J.
        • McCaul K.
        • Flicker L.
        A risk table to assist health practitioners assess and prevent the onset of depression in later life.
        Prev. Med. 2013; 57: 878-882