Hypertensive diseases of pregnancy including gestational hypertension and preeclampsia
continue to pose a major obstetric risk, responsible for around 12% of the global
burden of maternal mortality. Pregnancy-induced hypertensive disorders are unpredictable
in their onset and progression, and are curable only by termination of the pregnancy,
usually birth. There is increasing evidence that in addition to being a major cause
of preterm birth, intrauterine growth restriction and cerebral palsy, hypertensive
diseases of pregnancy can also lead to later adverse behavioral and cognitive consequences
for the offspring in childhood. Recent research from Finland extends these findings
through to old age, suggesting that far from being confined to neonatal and childhood
life, the adverse consequences for cognition and behavior can last until later life.
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References
- Hypertensive disorders in pregnancy and cognitive decline in the offspring up to old age.Neurology. 2012; 79: 1578-1582
- Hypertensive disorders in pregnancy and intellectual abilities in the offspring in young adulthood: the Helsinki Birth Cohort Study.Annals of Medicine. 2011; ([April 15 Early Online])
- Pregnancy-associated hypertensive disorders and adult cognitive function among danish conscripts.American Journal of Epidemiology. 2009; 170: 1025-1031
- Birth weight and psychological distress at age 45–51 years: results from the Aberdeen Children of the 1950s cohort study.British Journal of Psychiatry. 2005; 187: 21-28
- Early life predictors of childhood intelligence: evidence from the Aberdeen children of the 1950s study.Journal of Epidemiology and Community Health. 2005; 59: 656-663
Article info
Publication history
Published online: January 14, 2013
Received:
December 14,
2012
Identification
Copyright
© 2013 Elsevier Ireland Ltd. Published by Elsevier Inc. All rights reserved.
