Research Article| Volume 63, ISSUE 1, P67-72, May 20, 2009

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Race and health-related quality of life in midlife women in Baltimore, Maryland

  • Lisa Gallicchio
    The Prevention and Research Center, Weinberg Center for Women's Health and Medicine, Mercy Medical Center, Baltimore, MD 21202, United States

    Department of Epidemiology, Johns Hopkins Bloomberg School of Public Health, Baltimore, MD 21205, United States
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  • Susan Miller
    Department of Gynecology and Obstetrics, Johns Hopkins University School of Medicine, Baltimore, MD 21205, United States
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  • Howard Zacur
    Department of Gynecology and Obstetrics, Johns Hopkins University School of Medicine, Baltimore, MD 21205, United States
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  • Jodi A. Flaws
    Corresponding author. Tel.: +1 217 333 7933; fax: +1 217 244 1652.
    Department of Veterinary Biosciences, University of Illinois, 2001 S. Lincoln Ave., Room 3223, Urbana, IL 61802, United States
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      Only a few studies have examined the association between race/ethnicity and health-related quality of life (HRQOL) during midlife. Thus, the purpose of this study was to examine this association in the context of a population-based study of Caucasian and African-American women aged 45–54 years.


      Data from 626 pre- and peri-menopausal African-American and Caucasian women aged 45–54 years were analyzed. HRQOL was measured using Cantril's Self-Anchoring Ladder of Life, a validated measure of overall life satisfaction. Body mass index was determined using measured height and weight. Information on race and other variables such as education was based on self-report. Logistic regression models were constructed to examine the unadjusted and adjusted associations between race and low present HRQOL (≤6 on Cantril's Ladder of Life).


      In both the unadjusted and adjusted analyses, race was not significantly associated with low present HRQOL (unadjusted OR 1.57; 95% CI 0.93, 2.65; adjusted OR 0.82; 95% CI 0.42, 1.61). In the fully adjusted model, only the number of menopausal symptoms and self-rated health were significantly associated with present HRQOL.


      Findings from this population-based study suggest that race is not a statistically significant determinant of present HRQOL among midlife women.


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