Abstract
Objective
As chronic urticaria in pre-menopausal women was accompanied by lower serum concentration
of DHEA-S and because it had been known that endocrine profiles changed along with
ageing, in the present study we investigated DHEA-S behaviour in post-menopausal women
suffering from chronic idiopathic urticaria (CIU).
Methods
Serum concentration of DHEA-S was measured in 32 post-menopausal women, aged between
49 and 66, suffering from CIU, as well as in 30 healthy subjects matched for age,
body mass index, and years since menopause.
Results
No statistical difference in DHEA-S serum concentration was found between the CIU
patients and the controls (median 99.63 ug/dl versus 108.25 ug/dl, respectively).
Conclusions
The observations made recently and those of our previous results may point to the
existence of two different hormonal patterns of DHEA-S circulating concentration in
female patients suffering from CIU, depending on age of the disease onset. The scope
of the study has been limited however, due to the small number of subjects.
Keywords
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Article info
Publication history
Published online: July 16, 2007
Accepted:
June 19,
2007
Received in revised form:
May 19,
2007
Received:
September 14,
2006
Identification
Copyright
© 2007 Elsevier Ireland Ltd. Published by Elsevier Inc. All rights reserved.
