Abstract
Aim and setting: This study investigated correlations between insulinemia, insulin sensitivity, body
mass index, lipids and lipoproteins with intima-media thickness in a group of 25 (age
range 40–55 years) postmenopausal women (minimum duration of menopause 2 years) not
on hormone replacement treatment. Methodology: Uni and multivariate correlations showed a direct relationship between insulin pattern,
insulin sensitivity, body mass index, low density lipoproteins and increased intima-media
thickness. Results: Our multivariate correlation results revealed that intima-media thickness is influenced
by the associations of the different metabolic functions investigated. Therefore,
carotid wall intima-media thickness represents a dependent variable in postmenopausal
women for some metabolisms whose dysfunction leads to atherosclerosis. Conclusion: This multielement synergy is able to detect cardiovascular risk and may underlie
cardiovascular mortality in postmenopausal women.
Keywords
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Article info
Publication history
Accepted:
December 11,
2003
Received in revised form:
December 1,
2003
Received:
March 5,
2002
Identification
Copyright
© 2004 Elsevier Ireland Ltd. Published by Elsevier Inc. All rights reserved.
