To aim of this Cochrane review was to assess the efficacy, safety and acceptability
of food products, extracts and dietary supplements for the relief of vasomotor menopausal
symptoms e.g. hot flushes and night sweats. Included women were either perimenopausal
or postmenopausal women with spontaneous or surgical menopause; excluded women were
those who had used hormone therapy less than month ago or had a history of breast
cancer. Studies were randomised controlled comparisons of high levels of phytoestrogens
(e.g. at least 30 mg/d of isoflavones) for more than 12 weeks versus placebo, HT, no treatment or products
containing low levels of phytoestrogens.
Keywords
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References
- Phytoestrogens for menopausal vasomotor symptoms.Cochrane Database Syst Rev. 2013; (Art. No.: CD001395)https://doi.org/10.1002/14651858.CD001395.pub4
- Effects of genistein on hot flushes in early postmenopausal women: a randomized, double-blind EPT and placebo-controlled study.Menopause. 2004; 11: 400-404
- A natural S-Equol supplement alleviates hot flushes and other menopausal symptoms in equol nonproducing postmenopausal Japanese women.J Women Health. 2012; 21: 92-100
- Efficacy and safety of a special extract of Rheum rhaponticum (ERr 731) in perimenopausal women with climacteric complaints: a 12-week randomised double-blind placebo-controlled trial.Menopause. 2006; 13: 744-759
- The 2012 hormone therapy position statement of the North American Menopause Society.Menopause. 2012; 19: 257-271
Article info
Publication history
Published online: April 18, 2014
Identification
Copyright
© 2014 Elsevier Ireland Ltd. Published by Elsevier Inc. All rights reserved.
