Phytoestrogens for menopausal vasomotor symptoms: A Cochrane review summary

      To aim of this Cochrane review was to assess the efficacy, safety and acceptability of food products, extracts and dietary supplements for the relief of vasomotor menopausal symptoms e.g. hot flushes and night sweats. Included women were either perimenopausal or postmenopausal women with spontaneous or surgical menopause; excluded women were those who had used hormone therapy less than month ago or had a history of breast cancer. Studies were randomised controlled comparisons of high levels of phytoestrogens (e.g. at least 30 mg/d of isoflavones) for more than 12 weeks versus placebo, HT, no treatment or products containing low levels of phytoestrogens.


      To read this article in full you will need to make a payment

      Purchase one-time access:

      Academic & Personal: 24 hour online accessCorporate R&D Professionals: 24 hour online access
      One-time access price info
      • For academic or personal research use, select 'Academic and Personal'
      • For corporate R&D use, select 'Corporate R&D Professionals'


      Subscribe to Maturitas
      Already a print subscriber? Claim online access
      Already an online subscriber? Sign in
      Institutional Access: Sign in to ScienceDirect


        • Lethaby A.
        • Marjoribanks J.
        • Kronenberg F.
        • Roberts H.
        • Eden J.
        • Brown J.
        Phytoestrogens for menopausal vasomotor symptoms.
        Cochrane Database Syst Rev. 2013; (Art. No.: CD001395)
        • Crisafulli A.
        • Marini H.
        • Bitto A.
        • et al.
        Effects of genistein on hot flushes in early postmenopausal women: a randomized, double-blind EPT and placebo-controlled study.
        Menopause. 2004; 11: 400-404
        • Aso T.
        • Uchiyama S.
        • Matsumura Y.
        • et al.
        A natural S-Equol supplement alleviates hot flushes and other menopausal symptoms in equol nonproducing postmenopausal Japanese women.
        J Women Health. 2012; 21: 92-100
        • Heger M.
        • Ventskovskiy B.M.
        • Borzenko I.
        • et al.
        Efficacy and safety of a special extract of Rheum rhaponticum (ERr 731) in perimenopausal women with climacteric complaints: a 12-week randomised double-blind placebo-controlled trial.
        Menopause. 2006; 13: 744-759
        • North American Menopause Society
        The 2012 hormone therapy position statement of the North American Menopause Society.
        Menopause. 2012; 19: 257-271