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Abstract
Serum lipids and lipoproteins were assessed after treatment with 2 mg of oestradiol
valerate (E2V) and 10 μg of ethinyl oestreadiol (EE) in a group of 24 oophorectomised women in
a study with an open cross-over design.
E2V in this oral dose was quite inert in its effect on lipoprotein lipids. Ten micrograms
of EE is a dose which in most women is sufficient to alleviate post-menopausal vasomotor
symptoms. However, this low dose of EE increased serum triglycerides as a result of
increased levels in the ultracentrifugally isolated lipoprotein fractions. Increased
levels of serum and lipoprotein triglycerides are considered cardiovascular risk factors
in women.
Keywords
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Article info
Publication history
Accepted:
August 22,
1988
Received in revised form:
August 1,
1988
Received:
February 26,
1988
Identification
Copyright
© 1988 Published by Elsevier Inc.
