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Abstract
Serum oestradiol/oestrone ratios were measured during various oestrogen treatments
in castrated women. Oral oestriol succinate therapy (8 mg/day) caused little change
in the pre-treatment oestradiol/oestrone ratio. During oestradiol valerianate therapy
(2 mg/day) serum total oestrogens and the E2/E1 ratio were considerably increased. One day after the injection of 10 mg of oestradiol
valerianate and 2.5 mg of oestradiol benzoate + 10 mg of oestradiol phenylpropionate
the E2/E1 ratio was similar to the ratio in the middle of the normal ovulatory cycle. The change
in serum oestriol was rather small after oral doses of 8 mg of oestriol succinate
15, 30 and 120 min after the application.
Keywords
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References
- Concentration of unconjugated estrone and estradiol in peripheral plasma in nonpregnant women throughout the menstrual cycle, castrate and postmenopausal women and in men.J. Clin. Endocrinol. 1969; 29: 149-156
- Plasma levels of fractionated estrogens and pituitary hormones in endometrial carcinoma.Am. J. Obstet. Gynecol. 1976; 126: 638-647
- Ovarian production of estrogens in postmenopausal women.Int. J. Gynaecol. Obstet. 1980; 18: 93-98
- Serum oestriol, oestrone and oestradiol concentrations during oral oestriol succinate treatment in ovariectomized women.Maturitas. 1978; 1: 71-78
- Serum oestrone, oestradiol and oestriol concentrations during oral oestradiol valerate and oestriol succinate therapy in ovariectomized women.Maturitas. 1978; 1: 79-85
- Serum estrone, estradiol and estriol concentrations during oral hormone therapy after oophorectomy.Int. J. Gynaecol. Obstet. 1979; 16: 348-350
- Estrogen receptors and the estrone hypothesis in relation to endometrial and breast cancer.Gynecol. Oncol. 1974; 2: 228-238
- Plasma concentrations of unconjugated and conjugated estrogens and gonadotrophins following application of various estrogen preparations after oophorectomy and in the menopause.Maturitas. 1979; 1: 183-190
Article info
Publication history
Accepted:
May 13,
1981
Received:
January 20,
1981
Identification
Copyright
© 1981 Published by Elsevier Inc.