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Abstract
A study of the effects of a conjugated estrogen (Femipren) upon various climacteric symptoms, depression and anxiety scores and psycho-social factors in 120 women around
the menopause, was carried out in a Menopause Clinic.
In order to participate in this study, the women had to meet very strict criteria.
A climacteric symptom list, the MMPI and a psycho-social questionnaire were used for
assessment, and were employed before, during and at the end of 1 yr of hormone replacement
therapy.
Typical vasomotor and psychic symptoms changed significantly as did such factors as
self-image, optimism, perception of the future and satisfaction with personal appearance,
in those patients who received hormonal replacement therapy for 1 yr. As the psychological
factors changed only in those patients who received long-term estrogen therapy, a
tentative hypothesis of direct psychotropic effect of estrogen was formulated.
Keywords
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Article info
Publication history
Accepted:
March 22,
1979
Received:
October 25,
1978
Identification
Copyright
© 1979 Published by Elsevier Inc.