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Review| Volume 1, ISSUE 4, P279-285, June 1979

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Bone loss during oestriol therapy in postmenopausal women

DOI:https://doi.org/10.1016/0378-5122(79)90018-5
Bone loss during oestriol therapy in postmenopausal women
Previous ArticleCytologic evaluation of hormonal dynamic in the postmenopause
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      Abstract

      In contrast to all other oestrogens examined thus far oestriol hemisuccinate (12 mg/day) did not prevent bone loss in 28 postmenopausal women. The average bone loss, however, was somewhat less than expected from placebo studies, while the bone loss achieved by a group taking 4–6 mg/day was equal to that achieved by previous placebo groups. To be an effective agent for prevention of post-menopausal osteoporosis oestriol would have to be prescribed in daily doses considerably in excess of 12 mg.

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      Article info

      Publication history

      Accepted: February 7, 1979
      Received: December 11, 1978

      Identification

      DOI: https://doi.org/10.1016/0378-5122(79)90018-5

      Copyright

      © 1979 Published by Elsevier Inc.

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