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The following is an assessment of the maturation value (MV) based upon cytohormonal smears of postmenopausal or hysterectomized patients:
- 1.(1) There is a negative correlation between the MV and the number of postmenopausal years.
- 2.(2) There is a positive correlation between MV values higher than 60 and urinary excretion of estrogens.
- 3.(3) The MV is ideally suited to demonstrate the beneficial effect of various estrogens on the vaginal mucosa.
- 4.(4) Though its action is delayed, and necessitates a threshold dose of 33 μg/kg weight/wk, estriol might be considered as the drug of choice for a beneficial effect on the vaginal mucosa, because of its lack of endometrial action at this dosage.
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Accepted: November 8, 1978
Received: July 20, 1978
☆Presented at the Second International Congress on the Menopause, Jerusalem, Israel, 4–9 June 1978.
© 1979 Published by Elsevier Inc.