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Abstract
Research on the climacteric has largely concentrated on relationships between ovarian
insufficiency, oestrogen deficiency, and climacteric symptoms. Little attention has
been paid to those who have no symptoms. It is proposed, in addition to these relationships,
that the life events of this period are significantly involved; and that resultant
stress may contribute to oestrogen deficiency as opposed to physiologically normal
postmenopausal oestrogen levels.
In this preliminary study, two groups of women under conditions of relatively low
stress and high stress were tested over a period of 15 mth. They were rated on the
Hamilton Rating Scale for depression and anxiety and results were compared with the
corresponding total urinary oestrogen output. The results, which suggest a significant
relationship between stress related to depression and oestrogen levels in the menopause,
are discussed and compared with differing life circumstances of the subjects.
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Article info
Publication history
Accepted:
October 18,
1978
Received:
September 19,
1978
Identification
Copyright
© 1979 Published by Elsevier Inc.