Maturitas
Volume 63, Issue 2 , Pages 164-168, 20 June 2009

Patient scenario: A 53-year-old woman with hypoactive sexual desire disorder

  • Santiago Palacios

      Affiliations

    • Palacios Institute of Woman's Health, Antonio Acuña, 9, 28009 Madrid, Spain
    • Corresponding Author InformationCorresponding author. Tel.: +34 91 578 05 17; fax: +34 91 431 99 51.
  • ,
  • Alessandra Graziottin

      Affiliations

    • Centre of Gynaecology and Medical Sexology, H. San Raffaele Resnati, Via S. Croce 10/A, Milan, Italy

Received 23 January 2009; received in revised form 30 April 2009; accepted 1 May 2009. published online 25 May 2009.

Abstract 

Objective

To provide an expert review of the clinical management of hypoactive sexual desire disorder.

Method

The importance of diagnosing and providing therapeutic management for hypoactive sexual desire disorder will be explained with a case scenario which is resolved by drawing on original trial publications and meta-analyses published in English.

Results

Hypoactive sexual desire disorder (HSDD) is highly prevalent (9–16%) and has a strong impact on the quality of life of both women and their partners. Medical and sexual history, physical and laboratory examinations as well as validated questionnaires will help us make an accurate diagnosis. Treatment should begin by focusing on lifestyle and psychosexual therapy. Women randomized to oestrogen–testosterone transdermal patch combination or testosterone transdermal patch alone reported significantly increased frequency of satisfying sexual activity (p<0.05). Hormonal treatment with oestrogen and testosterone or with testosterone alone should be personalised, as should follow-up.

Conclusions

Guidelines for the medical management of hypoactive sexual desire disorder are now available and this starts by understanding the importance of this disorder and knowing that accurate diagnosis and treatment options exist.

Keywords: Female sexual dysfunction, Hypoactive sexual desire disorder, Menopause, Psychosexual therapy, Testosterone

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PII: S0378-5122(09)00148-0

doi:10.1016/j.maturitas.2009.05.002

Maturitas
Volume 63, Issue 2 , Pages 164-168, 20 June 2009