Maturitas
Volume 60, Issue 1 , Pages 19-30 , 20 May 2008

Insulin resistance, obesity and breast cancer risk

  • C. Pichard

      Affiliations

    • Unité de Gynécologie endocrinienne, Hôtel-Dieu, APHP, Université Paris-5, 1 Place du Parvis Notre-Dame, Paris, France
  • ,
  • G. Plu-Bureau

      Affiliations

    • Unité de Gynécologie endocrinienne, Hôtel-Dieu, APHP, Université Paris-5, 1 Place du Parvis Notre-Dame, Paris, France
  • ,
  • M. Neves-e Castro

      Affiliations

    • Clinica de Feminologia Holistica, Lisbonne, Portugal
  • ,
  • A. Gompel

      Affiliations

    • Unité de Gynécologie endocrinienne, Hôtel-Dieu, APHP, Université Paris-5, 1 Place du Parvis Notre-Dame, Paris, France
    • Corresponding Author InformationCorresponding author. Tel.: +33 142348099; fax: +33 143298766.

Received 1 November 2007 ,Revised 10 March 2008 ,Accepted 17 March 2008.

References 

  1. Lahmann PH, Hoffmann K, Allen N, et al. Body size and breast cancer risk: findings from the European Prospective Investigation into Cancer and Nutrition (EPIC). Int J Cancer. 2004;111(5):762–771
  2. Michels KB, Terry KL, Willett WC. Longitudinal study on the role of body size in premenopausal breast cancer. Arch Intern Med. 2006;166(21):2395–2402
  3. Van den Brandt PA, Spiegelman D, Yaun SS, et al. Pooled analysis of prospective cohort studies on height, weight, and breast cancer risk. Am J Epidemiol. 2000;152(6):514–527
  4. Shu XO, Jin F, Dai Q, et al. Association of body size and fat distribution with risk of breast cancer among Chinese women. Int J Cancer. 2001;94(3):449–455
  5. Baer HJ, Colditz GA, Rosner B, et al. Body fatness during childhood and adolescence and incidence of breast cancer in premenopausal women: a prospective cohort study. Breast Cancer Res. 2005;7(3):R314–R325
  6. Baer HJ, Rich-Edwards JW, Colditz GA, et al. Adult height, age at attained height, and incidence of breast cancer in premenopausal women. Int J Cancer. 2006;119(9):2231–2235
  7. Weiderpass E, Braaten T, Magnusson C, et al. Prospective study of body size in different periods of life and risk of premenopausal breast cancer. Cancer Epidemiol Biomarkers Prev. 2004;13(7):1121–1127
  8. Garland M, Hunter DJ, Colditz GA, et al. Menstrual cycle characteristics and history of ovulatory infertility in relation to breast cancer risk in a large cohort of US women. Am J Epidemiol. 1998;147(7):636–643
  9. Rich-Edwards JW, Goldman MB, Willett WC, et al. Adolescent body mass index and infertility caused by ovulatory disorder. Am J Obstet Gynecol. 1994;171(1):171–177
  10. Hartz AJ, Barboriak PN, Wong A, Katayama KP, Rimm AA. The association of obesity with infertility and related menstural abnormalities in women. Int J Obes. 1979;3(1):57–73
  11. Cui Y, Whiteman MK, Flaws JA, Langenberg P, Tkaczuk KH, Bush TL. Body mass and stage of breast cancer at diagnosis. Int J Cancer. 2002;98(2):279–283
  12. Garmendia ML, Pereira A, Alvarado ME, Atalah E. Relation between insulin resistance and breast cancer among Chilean women. Ann Epidemiol. 2007;17(6):403–409
  13. Wajchenberg BL. Subcutaneous and visceral adipose tissue: their relation to the metabolic syndrome. Endocrinol Rev. 2000;21(6):697–738
  14. Douchi T, Kuwahata R, Yamamoto S, Oki T, Yamasaki H, Nagata Y. Relationship of upper body obesity to menstrual disorders. Acta Obstet Gynecol Scand. 2002;81(2):147–150
  15. Kaaks R, Berrino F, Key T, et al. Serum sex steroids in premenopausal women and breast cancer risk within the European Prospective Investigation into Cancer and Nutrition (EPIC). J Natl Cancer Inst. 2005;97(10):755–765
  16. Muti P, Stanulla M, Micheli A, et al. Endogenous sex hormones and subsequent breast cancer in premenopausal women. Int J Cancer. 2004;112(2):312–318
  17. Eliassen AH, Missmer SA, Tworoger SS, et al. Endogenous steroid hormone concentrations and risk of breast cancer among premenopausal women. J Natl Cancer Inst. 2006;98(19):1406–1415
  18. Sonnenschein E, Toniolo P, Terry MB, et al. Body fat distribution and obesity in pre-and postmenopausal breast cancer. Int J Epidemiol. 1999;28(6):1026–1031
  19. Adams-Campbell LL, Nwankwo M, Ukoli F, Omene J, Haile GT, Kuller LH. Body fat distribution patterns and blood pressure in black and white women. J Natl Med Assoc. 1990;82(8):573–576
  20. Seidell JC, Cigolini M, Charzewska J, Ellsinger BM, Contaldo F. Regional obesity and serum lipids in European women born in 1948. A multicenter study. Acta Med Scand. 1988;723(Suppl.):189–197
  21. Huang Z, Willett WC, Colditz GA, et al. Waist circumference, waist:hip ratio, and risk of breast cancer in the Nurses’ Health Study. Am J Epidemiol. 1999;150(12):1316–1324
  22. Friedenreich CM. Review of anthropometric factors and breast cancer risk. Eur J Cancer Prev. 2001;10(1):15–32
  23. Schapira DV, Kumar NB, Lyman GH, Cox CE. Abdominal obesity and breast cancer risk. Ann Intern Med. 1990;112(3):182–186
  24. McCarty MF. A paradox resolved: the postprandial model of insulin resistance explains why gynoid adiposity appears to be protective. Med Hypotheses. 2003;61(2):173–176
  25. Snijder MB, Dekker JM, Visser M, et al. Larger thigh and hip circumferences are associated with better glucose tolerance: the Hoorn study. Obes Res. 2003;11(1):104–111
  26. Connolly BS, Barnett C, Vogt KN, Li T, Stone J, Boyd NF. A meta-analysis of published literature on waist-to-hip ratio and risk of breast cancer. Nutr Cancer. 2002;44(2):127–138
  27. Larsson SC, Mantzoros CS, Wolk A. Diabetes mellitus and risk of breast cancer: a meta-analysis. Int J Cancer. 2007;121(4):856–862
  28. Lawlor DA, Smith GD, Ebrahim S. Hyperinsulinaemia and increased risk of breast cancer: findings from the British Women's Heart and Health Study. Cancer Causes Control. 2004;15(3):267–275
  29. Schairer C, Hill D, Sturgeon SR, et al. Serum concentrations of IGF-I, IGFBP-3 and c-peptide and risk of hyperplasia and cancer of the breast in postmenopausal women. Int J Cancer. 2004;108(5):773–779
  30. Verheus M, Peeters PH, Rinaldi S, et al. Serum C-peptide levels and breast cancer risk: results from the European Prospective Investigation into Cancer and Nutrition (EPIC). Int J Cancer. 2006;119(3):659–667
  31. Sieri S, Pala V, Brighenti F, et al. Dietary glycemic index, glycemic load, and the risk of breast cancer in an Italian prospective cohort study. Am J Clin Nutr. 2007;86(4):1160–1166
  32. Micheli A, Muti P, Secreto G, et al. Markers of insulin resistance and sex steroid hormone activity in relation to breast cancer risk: a prospective analysis of abdominal adiposity, sebum production, and hirsutism. Cancer Causes Control. 2000;11(8):721–730
  33. Fasshauer M, Paschke R. Regulation of adipocytokines and insulin resistance. Diabetologia. 2003;46:1594–1603
  34. Tworoger SS, Eliassen AH, Kelesidis T, et al. Plasma adiponectin concentrations and risk of incident breast cancer. J Clin Endocrinol Metab. 2007;92(4):1510–1516
  35. Miyoshi Y, Funahashi T, Kihara S, et al. Association of serum adiponectin levels with breast cancer risk. Clin Cancer Res. 2003;9(15):5699–5704
  36. Chen DC, Chung YF, Yeh YT, et al. Serum adiponectin and leptin levels in Taiwanese breast cancer patients. Cancer Lett. 2006;237(1):109–114
  37. Mantzoros C, Petridou E, Dessypris N, et al. Adiponectin and breast cancer risk. J Clin Endocrinol Metab. 2004;89(3):1102–1107
  38. Hill AB. The environment and disease: association or causation?. Proc R Soc Med. 1965;58:295–300
  39. Hamelers IH, Steenbergh PH. Interactions between estrogen and insulin-like growth factor signaling pathways in human breast tumor cells. Endocr Relat Cancer. 2003;10(2):331–345
  40. Cascio S, Bartella V, Garofalo C, Russo A, Giordano A, Surmacz E. Insulin-like growth factor 1 differentially regulates estrogen receptor-dependent transcription at estrogen response element and AP-1 sites in breast cancer cells. J Biol Chem. 2007;282(6):3498–3506
  41. Chong YM, Williams SL, Elkak A, Sharma AK, Mokbel K. Insulin-like growth factor 1 (IGF-1) and its receptor mRNA levels in breast cancer and adjacent non-neoplastic tissue. Anticancer Res. 2006;26(1A):167–173
  42. Baik I, Devito WJ, Ballen K, et al. Association of fetal hormone levels with stem cell potential: evidence for early life roots of human cancer. Cancer Res. 2005;65(1):358–363
  43. Savarese TM, Strohsnitter WC, Low HP, et al. Correlation of umbilical cord blood hormones and growth factors with stem cell potential: implications for the prenatal origin of breast cancer hypothesis. Breast Cancer Res. 2007;9(3):R29
  44. Park SK, Kang D, McGlynn KA, Garcia-Closas M, Kim Y, Yoo KY, et al. Intrauterine environments and breast cancer risk: meta-analysis and systematic review. Breast Cancer Res. 2008;10(1):R8
  45. Schernhammer ES, Holly JM, Hunter DJ, et al. Insulin-like growth factor-I, its binding proteins (IGFBP-1 and IGFBP-3), and growth hormone and breast cancer risk in the Nurses Health Study II. Endocr Relat Cancer. 2006;13:583–592
  46. Salpeter SR, Walsh JM, Ormiston TM, Greyber E, Buckley NS, Salpeter EE. Meta-analysis: effect of hormone-replacement therapy on components of the metabolic syndrome in postmenopausal women. Review. Diabetes Obes Metab. 2006;8(5):538–554
  47. Michels KB, Xue F. Role of birthweight in the etiology of breast cancer. Int J Cancer. 2006;119(9):2007–2025
  48. Campagnoli C, Abbà C, Ambroggio S, Peris C. Differential effects of progestins on the circulating IGF-I system. Review. Maturitas. 2003;46(Suppl. 1):S39–S44
  49. Krebs EE, Taylor BC, Cauley JA, Stone KL, Bowman PJ, Ensrud KE. Measures of adiposity and risk of breast cancer in older postmenopausal women. J Am Geriatr Soc. 2006;54(1):63–69
  50. Eliassen AH, Colditz GA, Rosner B, Willett WC, Hankinson SE. Adult weight change and risk of postmenopausal breast cancer. JAMA. 2006;296(2):193–201
  51. Tworoger SS, Eliassen AH, Missmer SA, et al. Birthweight and body size throughout life in relation to sex hormones and prolactin concentrations in premenopausal women. Cancer Epidemiol Biomarkers Prev. 2006;15(12):2494–2501
  52. Harvie M, Howell A, Vierkant RA, et al. Association of gain and loss of weight before and after menopause with risk of postmenopausal breast cancer in the Iowa women's health study. Cancer Epidemiol Biomarkers Prev. 2005;14(3):656–661
  53. Eng SM, Gammon MD, Terry MB, et al. Body size changes in relation to postmenopausal breast cancer among women onLong Island, New York. Am J Epidemiol. 2005;162(3):229–237
  54. Morimoto LM, White E, Chen Z, et al. Obesity, body size, and risk of postmenopausal breast cancer: the Women's Health Initiative (United States). Cancer Causes Control. 2002;13(8):741–751
  55. Furberg AS, Veierød MB, Wilsgaard T, Bernstein L, Thune I. Serum high-density lipoprotein cholesterol, metabolic profile, and breast cancer risk. J Natl Cancer Inst. 2004;96(15):1152–1160

PII: S0378-5122(08)00100-X

doi: 10.1016/j.maturitas.2008.03.002

Maturitas
Volume 60, Issue 1 , Pages 19-30 , 20 May 2008