Maturitas
Volume 59, Issue 3 , Pages 242-248 , 20 March 2008

Obesity, estrone, and coronary artery disease in postmenopausal women

  • T.C.B.F. Silva

      Affiliations

    • Heart Institute (InCor), University of São Paulo Medical School, 05468-000 São Paulo, Brazil
  • ,
  • E. Barrett-Connor

      Affiliations

    • Department of Family and Preventive Medicine, School of Medicine, University of California, San Diego, La Jolla, CA, United States
  • ,
  • J.A.F. Ramires

      Affiliations

    • Heart Institute (InCor), University of São Paulo Medical School, 05468-000 São Paulo, Brazil
  • ,
  • A.P. Mansur

      Affiliations

    • Heart Institute (InCor), University of São Paulo Medical School, 05468-000 São Paulo, Brazil
    • Corresponding Author InformationCorresponding author. Tel.: +55 11 30695387; fax: +55 11 30695348.

Received 21 June 2007 ,Revised 28 November 2007 ,Accepted 28 January 2008.

References 

  1. Mansur AP, Favarato D, Souza MFM, et al. Tendência do risco de morte por doenças circulatórias no Brasil de 1979 a 1996. Arq Bras Cardiol. 2001;76:497–510
  2. Ross R. Atherosclerosis—an inflammatory disease. N Engl J Med. 1999;340:115–126
  3. Kuulasmaa K, Tunstall-Pedoe H, Dobson A, et al. Estimation of contribution of changes in classic risk factors to trends in coronary-event rates across the WHO MONICA Project populations. Lancet. 2000;355:675–687
  4. Stangl V, Baumann G, Stangl K. Coronary atherogenic risk factors in women. Eur Heart J. 2002;23:1738–1752
  5. Gruber CJ, Tschugguel W, Schneeberger C, Huber JC. Production and actions of estrogens. N Engl J Med. 2002;346:340–352
  6. Meza-Munoz DE, Fajardo ME, Perez-Luque EL, Malacara JM. Factors associated with estrogen receptors-alpha (ER-alpha) and -beta (ER-beta) and progesterone receptor abundance in obese and non obese pre- and postmenopausal women. Steroids. 2006;71:498–503
  7. Brown L, Hoong I, Doggrell AS. The heart as a target for oestrogens. Heart Lung Circ. 2000;9:113–125
  8. Mendelsohn ME. Protective effects of estrogen on the cardiovascular system. Am J Cardiol. 2002;89:12E–18E
  9. Lerner DJ, Kannel WB. Patterns of coronary heart disease morbidity and mortality in the sexes: a 26-year follow-up of the Framingham population. Am Heart J. 1986;111:383–390
  10. Kamat A, Hinshelwood MM, Murry BA, Mendelson CR. Mechanisms in tissue-specific regulation of estrogen biosynthesis in humans. Trends Endocrinol Metab. 2002;13:122–128
  11. Puche C, Jose M, Cabero A, Meseguer A. Expression and enzymatic activity of the P450c17 gene in human adipose tissue. Eur J Endocrinol. 2002;146:223–229
  12. Lukanova A, Lundin E, Zeleniuch-Jacquotte A, et al. Body mass index, circulating levels of sex-steroid hormones, IGF-I and IGF-binding protein-3: a cross-sectional study in healthy women. Eur J Endocrinol. 2004;150:161–171
  13. Flegal KM, Graubard BI, Williamson DF, Gail MH. Excess deaths associated with underweight, overweight, and obesity. JAMA. 2005;293:1861–1867
  14. Romero-Corral A, Montori VM, Somers VK, et al. Association of bodyweight with total mortality and with cardiovascular events in coronary artery disease: a systematic review of cohort studies. Lancet. 2006;368:666–678
  15. Lakka HM, Laaksonen DE, Lakka TA, et al. The metabolic syndrome and total and cardiovascular disease mortality in middle-aged men. JAMA. 2002;288:2709–2716
  16. Mosca L, Barret-Connor E, Wenger NK, et al. Design and methods of the Raloxifene Use for The Heart (RUTH) study. Am J Cardiol. 2001;88:392–395
  17. American Diabetes Association: diagnosis and classification of Diabetes Mellitus 2006. Diabetes Care. 2006;29(Suppl. S):S43–S48
  18. The Seventh Report of the Joint National Committee on Prevention, Detection, Evaluation and Treatment of High Blood Pressure. JAMA. 2003;289:2560–2572
  19. III Diretrizes Brasileiras Sobre Dislipidemias e Diretriz de Prevenção da Aterosclerose do Departamento de Aterosclerose da Sociedade Brasileira de Cardiologia. Arq Bras Cardiol. 2001;77:4–8
  20. World Health Organization. Guidelines for the conduct of the tobacco smoking surveys of the general population: report of a meeting. Geneva; 1992 (N/WHO/SMO/83.4).
  21. Obesity: preventing and managing the global epidemic. Report of a WHO Consultation Technical Report Series no. 894. Geneva: World Health Organization; 2000.
  22. Friedewald WT, Levy RI, Fredrickson DS. Estimation of the concentration of low-density lipoprotein cholesterol in plasma, without use of the preparative ultracentrifugation. Clin Chem. 1972;18:499–509
  23. http://www.cdc.gov/nchs/products/pubs/pubd/hestats/3and4/overweight.htm (assessed in June 15, 2007).
  24. Bender R, Zeeb H, Schwarz M, Jockel KH, Berger M. Causes of death in obesity: relevant increase in cardiovascular but not in all-cancer mortality. J Clin Epidemiol. 2006;59:1064–1071
  25. McGee DL, et al. Body mass index and mortality: a meta-analysis based on person-level data from twenty-six observational studies. Ann Epidemiol. 2005;15:87–97
  26. Gregg EW, Cheng YJ, Cadwell BL, et al. Secular trends in cardiovascular disease risk factors according to body mass index in US adults. JAMA. 2005;293:1868–1874
  27. Ridker PM, Hennekens CH, Buring JE, Rifai N. C-reactive protein and other markers of inflammation in the prediction of cardiovascular disease in women. N Engl J Med. 2000;342:836–843
  28. Yudkin JS, Stehouwer CD, Emeis JJ, Coppack SW. C-reactive protein in healthy subjects: associations with obesity, insulin resistance, and endothelial dysfunction: a potential role for cytokines originating from adipose tissue?. Arterioscler Thromb Vasc Biol. 1999;19:972–978
  29. Castracane VD, Kraemer GR, Ogden BW, Kraemer RR. Interrelationships of serum estradiol, estrone, and estrone sulfate, adiposity, biochemical bone markers, and leptin in postmenopausal women. Maturitas. 2006;53:217–225
  30. Mudali S, et al. Endogenous postmenopausal hormones and serum lipids: the atherosclerosis risk in communities study. J Clin Endocrinol Metab. 2005;90:1202–1209
  31. Simon JA, Hsia J, Cauley JA, et al. Postmenopausal hormone therapy and risk of stroke: The Heart and Estrogen-progestin Replacement Study (HERS). Circulation. 2001;103:638–642
  32. Rossouw JE, et al. Risks and benefits of estrogen plus progestin in healthy postmenopausal women: principal results from the Women's Health Initiative randomized controlled trial. JAMA. 2002;288:321–333
  33. Wu J, Oka J, Higuchi M, et al. Cooperative effects of isoflavones and exercise on bone and lipid metabolism in postmenopausal Japanese women: a randomized placebo-controlled trial. Metabolism. 2006;55:423–433

PII: S0378-5122(08)00034-0

doi: 10.1016/j.maturitas.2008.01.008

Maturitas
Volume 59, Issue 3 , Pages 242-248 , 20 March 2008