Maturitas
Volume 57, Issue 1 , Pages 23-26 , 20 May 2007

Estrogen, estrogen treatment and the post-reproductive woman's brain

  • Frederick Naftolin

      Affiliations

    • Department of Obstetrics and Gynecology New York University, New York 10016, USA
    • Corresponding Author InformationCorresponding author.
    • ,
  • Dolores Malaspina

      Affiliations

    • Department of Psychiatry New York University, New York 10016, USA

References 

  1. Naftolin F. Brain aromatization of androgens. J Reprod Med. 1994;39:257–261
  2. Szego CM. Mechanisms of hormone action: parallels in receptor-mediated signal propagation for steroid and peptide effectors. Life Sci. 1984;35:2383–2396
  3. Garcia-Segura LM, Olmos G, Tranque P, Naftolin F. Rapid effects of gonadal steroids upon hypothalamic neuronal membrane ultrastructure. J Steroid Biochem. 1987;27:615–623
  4. Simoncini T, Scorticati C, Mannella P, et al. Estrogen receptor alpha interacts with Galpha13 to drive actin remodeling and endothelial cell migration via the RhoA/Rho kinase/moesin pathway. Mol Endocrinol. 2006;20:1756–1771
  5. Simerly RB, Chang C, Muramatsu M, Swanson LW. Distribution of androgen and estrogen receptor mRNA-containing cells in the rat brain: an in situ hybridization study. J Comp Neurol. 1990;294:76–95
  6. Mor G, Nilsen J, Horvath T, Bechmann I, Garcia-Segura LM, Naftolin F. Estrogen microglia: a regulatory system that affects the brain. J Neurobiol. 1999;40:484–496
  7. Silva I, Mor G, Naftolin F. Estrogen and the aging brain. Maturitas. 2001;38:95–100
  8. Lavy G, Whitten PL, Naftolin F. Introduction to vertebrate reproductive endocrinology. In:  Pang PKT,  Schreibman MP editor. Vertebrate endocrinology: fundamentals and biomedical implications. vol. 4:New York: Academic Press; 1991;p. 1–22
  9. Naftolin F, Richman S. Menopause: lack of Darwinian adaptation drives its physiology. In:  Schneider HPG,  Naftolin F editor. Climacteric medicine—where do we go?. Abingdon, UK: Parthenon Publishing; 2005;p. 4–8
  10. Harman SM, Brinton EA, Clarkson T, et al. Is the WHI relevant to HRT started in the perimenopause?. Endocrine. 2004;24:195–202

PII: S0378-5122(07)00066-7

doi: 10.1016/j.maturitas.2007.02.005

Maturitas
Volume 57, Issue 1 , Pages 23-26 , 20 May 2007

Article Tools

* Image Usage & Resolution