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Maturitas
Volume 55
, Pages S92-S100
, 1 November 2006
Plant extracts for the treatment of menopausal women: Safe?
References
- . A clinician's review of the WHI-related literature. Int J Fertil Womens Med. 2004;49:252–267
- . Menopausal hormone therapy: currently no evidence for cardiac protection. Pediatr Blood Cancer. 2005;44:625–629
- . HRT as secondary prevention of cardiovascular disease. Maturitas. 2004;47:315–318
- . The Cimicifuga preparation BNO 1055 vs. conjugated estrogens in a double-blind placebo-controlled study: effects on menopause symptoms and bone markers. Maturitas. 2003;44(Suppl. 1):S67–S77
- . Efficacy and safety of isopropanolic black cohosh extract for climacteric symptoms. Obstet Gynecol. 2005;105:1074–1083
- . Cimicifuga racemosa dried ethanolic extract in menopausal disorders: a double-blind placebo-controlled clinical trial. Maturitas. 2005;51:397–404
- Isopropanolic extract of black cohosh stimulates osteoprotegerin production by human osteoblasts. J Bone Miner Res. 2005;20:2036–2043
- . Pharmacology of Cimicifuga racemosa extract BNO 1055 in rats: bone, fat and uterus. Maturitas. 2003;44(Suppl. 1):S39–S50
- . Effects of estradiol-17ß, testosterone and a black cohosh preparation on bone and prostate in orchidectomized rats. Maturitas. 2005;51:177–186
- Dietary soy protein and isoflavones: minimal beneficial effects on bone and no effect on the reproductive tract of sexually mature ovariectomized Sprague–Dawley rats. Menopause. 2005;12:165–173
- . Dietary soy protein and isoflavones: no effect on the reproductive tract and minimal positive effect on bone resorption in the intact female Fischer 344 rat. Food Chem Toxicol. 2005;43:945–949
- Dietary soy protein and isoflavones have no significant effect on bone and a potentially negative effect on the uterus of sexually mature intact Sprague–Dawley female rats. Menopause. 2005;12:291–298
- Comparative effect of soy protein, soy isoflavones, and 17 beta-estradiol on bone metabolism in adult ovariectomized rats. J Bone Miner Res. 2005;20:828–839
- . Phytoestrogens and carcinogenesis—differential effects of genistein in experimental models of normal and malignant rat endometrium. Hum Reprod. 2001;16:997–1006
- The differential ability of the phytoestrogen genistein and of estradiol to induce uterine weight and proliferation in the rat is associated with a substance specific modulation of uterine gene expression. Mol Cell Endocrinol. 2004;221:21–32
- . Sensitivity of the immature rat uterotrophic assay to mixtures of estrogens. Environ Health Perspect. 2004;112:575–582
- . Dietary genistein stimulates growth of estrogen-dependent breast cancer tumors similar to that observed with genistein. Carcinogenesis. 2001;22:1667–1673
- Dietary genistein results in larger MNU-induced, estrogen-dependent mammary tumors following ovariectomy of Sprague–Dawley rats. Carcinogenesis. 2004;25:211–218
- . Physiological concentrations of dietary genistein dose-dependently stimulate growth of estrogen-dependent human breast cancer (MCF-7) tumors implanted in athymic nude mice. J Nutr. 2001;131:2957–2962
- . Phytoestrogens and their human metabolites show distinct agonistic and antagonistic properties on estrogen receptor {alpha} (ER{alpha})and ER{beta} in human cells. Toxicol Sci. 2004;81:530–531
- . Estrogen receptor-alpha mediates the detrimental effects of neonatal diethylstilbestrol (DES) exposure in the murine reproductive tract. Toxicology. 2004;205:55–63
- Estrogen receptor alpha is required for mammary development and the induction of mammary hyperplasia and epigenetic alterations in the aromatase transgenic mice. J Steroid Biochem Mol Biol. 2005;95:9–15
- Differential regulation of estrogen receptor (ER)alpha and ERbeta in primate mammary gland. J Clin Endocrinol Metab. 2005.;90:435–444
- . Reflections on the discovery and significance of estrogen receptor beta. Endocr Rev. 2005;26:465–478
- . Estrogen receptor null mice: what have we learned and where will they lead us?. Endocr Rev. 1999;20:358–417
- . The endocrine effects of constituents of Cimicifuga racemosa. 2. In vitro binding of constituents to estrogen receptors. Planta Med. 1985;316–319
- . Effects of extracts from Cimicifuga racemosa on gonadotropin release in menopausal women and ovariectomized rats. Planta Med. 1991;57:420–424
- Evidence for selective estrogen receptor modulator activity in a black cohosh (Cimicifuga racemosa) extract: comparison with estradiol-17beta. Eur J Endocrinol. 2003;149:351–362
- . In vitro effects of the Cimicifuga racemosa extract BNO 1055. Maturitas. 2003;44(Suppl. 1):S31–S38
- Black cohosh acts as a mixed competitive ligand and partial agonist of the serotonin receptor. J Agric Food Chem. 2003;51:5661–5670
- Cimipronidine, a cyclic guanidine alkaloid from Cimicifuga racemosa. J Nat Prod. 2005;68:1266–1270
- Phytoestrogen cimicifugoside-mediated inhibition of catecholamine secretion by blocking nicotinic acetylcholine receptor in bovine adrenal chromaffin cells. J Pharmacol Exp Ther. 2004;309:641–649
- . Cimicifuga racemosa extract BNO 1055 inhibits proliferation of the human prostate cancer cell line LNCaP. Phytomedicine. 2005;12:178–182
- . Inhibitory aryl hydrocarbon receptor-estrogen receptor alpha cross-talk and mechanisms of action. Chem Res Toxicol. 2003;16:807–816
- . ER alpha-AHR-ARNT protein–protein interactions mediate estradiol-dependent transrepression of dioxin-inducible gene transcription. J Biol Chem. 2005;280:21607–21611
- . Morphological changes induced by oral 8-Prenylnaringenin long-term treatment in uterus, vagina and mammary gland of castrated rats. Menopause. 2006;13:669–677
- . Hormone-induced protection against breast cancer. J Mammary Gland Biol Neoplasia. 2002;7:77–92
- . Morphometric evaluation of effects of two sex steroids on mammary gland of female rats. Maturitas. 2005;51:370–379
- . Changes with age in levels of serum gonadotropins, prolactin and gonadal steroids in prepubertal male and female rats. Endocrinology. 1975;97:898–907
- Effects of hypothyroidism on the estrous cycle and reproductive hormones in mature female rat. Eur J Pharmacol. 2004;486:343–348
- Comparison of the ligand binding specificity and transcript tissue distribution of estrogen receptors alpha and beta. Endocrinology. 1997;138:863–870
- Comparing the pharmacokinetics of daidzein and genistein with the use of 13C-labeled tracers in premenopausal women. Am J Clin Nutr. 2003;77:411–419
- . Di Renzo GC. Endometrial effects of long-term treatment with phytoestrogens: a randomized, double-blind, placebo-controlled study. Fertil Steril. 2004;82:145–148quiz 265
- . Phytoestrogens for treatment of menopausal symptoms: a systematic review. Obstet Gynecol. 2004;104:824–836
- . Tissue-selective effects of continuous release of 2-hydroxyestrone and 16 alpha-hydroxyestrone on bone, uterus and mammary gland in ovariectomized growing rats. J Endocrinol. 2001;170:165–174
- . Postmenopausal hot flushes: a disorder of thermoregulation. Maturitas. 1980;2:101–107
- . Botanical and dietary supplements for menopausal symptoms: what works, what does not. J Womens Health (Larchmt). 2005;14:634–649
PII: S0378-5122(06)00243-X
doi: 10.1016/j.maturitas.2006.06.021
© 2006 Elsevier Ireland Ltd. All rights reserved.
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Maturitas
Volume 55
, Pages S92-S100
, 1 November 2006
