Maturitas
Volume 55, Issue 2 , Pages 132-141 , 20 September 2006

Antigens and granularity of blood monocytes in relation to inflammatory markers and lipids in postmenopausal women

  • K. Zouaoui Boudjeltia

      Affiliations

    • Laboratoire de Médecine Expérimentale (ULB 222 Unit), ISPPC Hopital André Vesale, Montigny-Le-Tilleul, Belgium
    • Corresponding Author InformationCorresponding author at: Laboratoire de Médecine Expérimentale (Université libre de Bruxelles, Unit 222), ISPPC, CHU André Vésale, 706, route de Gozée, 6110 Montigny-le-Tilleul, Belgium. Tel.: +32 71 921511; fax: +32 71 924710.
    • ,
  • C. Gregoir

      Affiliations

    • Rheumatology Department, ISPPC Hopital André Vesale, Montigny-Le-Tilleul, Belgium
    • ,
  • M. Guillaume

      Affiliations

    • Laboratoire de Médecine Expérimentale (ULB 222 Unit), ISPPC Hopital André Vesale, Montigny-Le-Tilleul, Belgium
    • ,
  • C. Remacle

      Affiliations

    • Intitute of Life Sciences, Laboratoire de Biologie Cellulaire, Université Catholique de Louvain, Louvain-La-Neuve, Belgique
    • ,
  • P. Piro

      Affiliations

    • Laboratoire de Médecine Expérimentale (ULB 222 Unit), ISPPC Hopital André Vesale, Montigny-Le-Tilleul, Belgium
    • ,
  • C. Garbar

      Affiliations

    • Laboratoire de Médecine Expérimentale (ULB 222 Unit), ISPPC Hopital André Vesale, Montigny-Le-Tilleul, Belgium
    • ,
  • J. Ducobu

      Affiliations

    • Internal Medicine Department, CHU Tivoli, La louvière, Belgium
    • ,
  • N. Moguilevsky

      Affiliations

    • Service de Génétique Appliquée, Institut de Biologie Moléculaire et Médicale, ULB, Gosselies, Belgium
    • ,
  • M. Vanhaeverbeek

      Affiliations

    • Laboratoire de Médecine Expérimentale (ULB 222 Unit), ISPPC Hopital André Vesale, Montigny-Le-Tilleul, Belgium
    • ,
  • P. Delree

      Affiliations

    • Institut de Pathologie et de Génétique, Loverval, Belgique
    • ,
  • D. Brohee

      Affiliations

    • Laboratoire de Médecine Expérimentale (ULB 222 Unit), ISPPC Hopital André Vesale, Montigny-Le-Tilleul, Belgium

Received 11 July 2005 ,Revised 9 December 2005 ,Accepted 13 December 2005.

References 

  1. Pfeilshifter J, Koditz R, Pfohl M, Schatz H. Changes in proinflammatory cytokine activity after menopause. Endocr Rev. 2002;23:90–119
  2. Bittner V. Lipoprotein abnormalities related to women's health. Am J Cardiol. 2002;90(8A):77–84
  3. Ben-Hur H, Mor G, Insler V, et al. Menopause is associated with a significant increase in blood monocyte number and a relative decrease in the expression of estrogen receptors in human peripheral monocytes. AJRI. 1995;34:363–369
  4. Dorffel Y, Franz S, Pruss A, et al. Preactivated monocytes from hypertensive patients as a factor for atherosclerosis?. Atherosclerosis. 2001;157:151–160
  5. Rothe G, Gabriel H, Kovacs E, et al. Peripheral blood mononuclear phagocyte subpopulations as cellular markers in hypercholesterolemia. Arterioscl Throm Vasc Biol. 1996;16:1437–1447
  6. Patino R, Ibarra J, Rodriguez A, et al. Circulating monocytes in patients with diabetes mellitus, arterial disease, and increased CD14 expression. Am J Cardiol. 2000;85:1288–1291
  7. Pacifici R, Brown C, Puscheck E, et al. Effect of surgical menopause and estrogen replacement on cytokine release from human blood mononuclear cells. Proc Natl Acad Sci. 1991;88:5134–5138
  8. Belge KU, Dayyani F, Horelt A, et al. The proinflammatory CD14+CD16+DR++ monocytes are a major source of TNF. J Immunol. 2002;168:3536–3542
  9. Draude G, Von Hundelshausen , Frankenberger M, Ziegler-Heitebrock HWL, Weber C. Distinct scavenger receptor expression and function in human CD14+/CD16+ monocyte subset. Am J Physiol (Heart Circ Physiol). 1999;276:H1144–H1149
  10. Ballou SP, Lozanski G. Induction of inflammatory cytokine release from cultured human monocytes by C-reactive protein. Cytokine. 1992;4:361–368
  11. Sitrin RG, Pan PM, Srikanth S, Todd RF. Fibrinogen activates NF-κβ transcription factors in mononuclear phagocytes. J Immunol. 1998;161:1462–1470
  12. Jerome WG, Cash C, Webber R, Horton R, Yancey PG. Lysosomal lipid accumulation from oxidized low density lipoprotein is correlated with hypertrophy of the Golgi apparatus and trans-golgi network. J Lipid Res. 1998;39:1362–1371
  13. Mori M, Itabe H, Higashi Y, et al. Foam cell formation containing lipids droplet enriched with free cholesterol by hyperlipemic serum. J Lipid Res. 2001;42:1771–1781
  14. Dresel H, Via DP, Stöhr M, et al. Observations on leukocytes from patients with severe familial hypercholesterolemia. Arteriosclerosis. 1986;6:259–264
  15. Ambrosch A, Mühlen I, Kope D, et al. LDL size distribution in relation to insulin sensitivity and lipoprotein pattern in young and healthy subjects. Diabetes Care. 1998;12:2077–2084
  16. Zouaoui Boudjeltia K, Guillaume M, Gregoir C, et al. Plasma fibrinolytic capacity in postmenopausal women is related with the differentiation state of blood monocytes. Atherosclerosis. 2002;3(Supplements):244;(abstract)
  17. Moguilevsky N, Zouaoui Boudjeltia K, Babar S, et al. Monoclonal antibodies against LDL progressively oxidized by myeloperoxidase react with ApoB-100 protein moiety and human atherosclerotic lesions. Biochem Biophys Res Commun. 2004;323:1223–1228
  18. Havel RJ, Eder HA, Bragdon JH. The distribution and chemical composition of ultracentrifugally separated lipoproteins in human serum. J Clin Invest. 1955;34:1345–1353
  19. Moguilevsky N, Garcia-Quintana L, Jacquet A, et al. Structural and biological properties of biologically active human recombinant myeloperoxidase produced by Chinese Hamster Ovary cells in culture. Eur J Biochem. 1991;197:605–614
  20. Rigby WF, Shen L, Ball ED, Guyre PM, Fanger MW. Differentiation of a human monocytic cell line by 1,25-dihydroxivitamin D3 (calcitriol): a morphologic, phenotypic, and functional analysis. Blood. 1984;64:1110–1115
  21. Rossi P, Chini L, Fattorossi A, et al. 1,25-Dihydroxivitamin D3 and phorbol esters (TPA) may induce select in vitro differentiation pathways in the HL60 promyelocytic cell line. Clin Immunol Immunopathol. 1987;44:308–316
  22. Ertel W, Krombach F, Kremer JP, et al. Mechanisms of cytokine cascade activation in patients with sepsis: normal cytokine transcription despite reduced CD14 receptor expression. Surgery. 1993;114:243–250
  23. Gotzinger P, Sautner T, Spittler A, et al. Severe acute pancreatitis causes alterations in HLA-DR and CD14 expression on peripheral blood monocytes independently of surgical treatment. Eur J Surg. 2000;166:628–632
  24. Raychaudhuri B, Bonfield TL, Malur A, et al. Circulating monocytes from patients with primary pulmonary hypertension are hyporesponsive. Clin Immunol. 2002;104:191–198
  25. Scheinbenbogen C, Andreesen R. Developmental regulation of the cytokine repertoire in human macrophages: IL-6, IL-1, TNF and MCS-F. J Leukoc Biol. 1991;50:35–42
  26. Murphy FJ, Reen DJ. Differential expression of function-related antigens on newborn and adult monocyte subpopulations. Immunology. 1996;89:587–591
  27. Heinecke JW. New approaches to diagnosis and prognosis in atherosclerosis. Am J Cardiol. 2003;91:12A–16A
  28. Shishebor M, Brennan ML, Aviles RJ, et al. Statins promote potent systemic antioxidant effects through specific inflammatory pathways. Circulation. 2003;108:426–431
  29. Itabe H. Oxidized low-density lipoproteins: what is understood and what remains to be clarified. Biol Pharm Bull. 2003;26:1–9
  30. Zouaoui Boudjeltia K, Moguilevsky N, Legssyer I, et al. Oxidation of low density lipoproteins by myeloperoxidase at the surface of endothelial cells: an additional mechanism to subendothelium oxidation. Biochem Biophys Res Commun. 2004;325:434–438
  31. Pajkrt D, Doran JE, Koster F, et al. Antiinflammatory effects of reconstituted high-density lipoprotein during human endotoxemia. J Exp Med. 1996;184:1601–1608
  32. Hedrick CC, Castellani LW, Wong H, Lusis AJ. In vivo interactions of apoA-II, apoA-1, and hepatic lipase contributing to HDL structure and antiatherogenic functions. J Lipid Res. 2001;42:563–570
  33. Tschaikowsky K, Hedwig-Geissing M, Schiele A, Bremer F, Schywalsky M, Schuttler J. Coincidence of pro- and anti-inflammatory responses in the early phase of severe sepsis: longitudinal study of mononuclear histocompatibility leukocyte antigen-DR expression, procalcitonin, C-reactive protein, and changes in T-cell subsets in septic and postoperative patients. Crit Care Med. 2002;30:1015–1023
  34. Roselaar SE, Schonfeld G, Daugherty A. Enhanced development of atherosclerosis in cholesterol-fed rabbits by suppression of cell-mediated immunity. J Clin Invest. 1995;96:1389–1394
  35. Emeson EE, Shen ML. Accelerated atherosclerosis in hyperlipemic C57BL/6 mice treated with cyclosporin A. Am J Pathol. 1993;142:1906–1915
  36. Fyfe AI, Qiao JH, Lusis AJ. Immune-deficient mice develop typical atherosclerotic fatty streaks when fed and atherogenic diet. J Clin Invest. 1994;94:2516–2520
  37. Theilmeier G, Lenaerts T, Remacle C, Collen D, Vermylen J, Hoylaerts MF. Circulating activated platelets assist THP-1 monocytoid/endothelial cells interaction under shear stress. Blood. 1999;94:2725–2734
  38. Weber C, Belge KU, Hundelshausen , et al. Differential chemokine receptor expression and function in human monocytes subpopulations. J Leukoc Biol. 2000;67:699–704

PII: S0378-5122(06)00002-8

doi: 10.1016/j.maturitas.2005.12.009

Maturitas
Volume 55, Issue 2 , Pages 132-141 , 20 September 2006

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