Maturitas
Volume 63, Issue 2 , Pages 142-148, 20 June 2009

Mechanism of androgen receptor action

Gynaecology Research Unit, University Hospitals of Leicester, Victoria Building, Leicester Royal Infirmary, Leicester LE1 5WW, United Kingdom

Received 27 January 2009; received in revised form 9 March 2009; accepted 11 March 2009. published online 06 April 2009.

Abstract 

Recent research provides a much more detailed understanding of the role of the androgen receptor in normal human development and physiology, its structure, and its functioning. This review discusses genomic and non-genomic actions of the androgen receptor, as well as their co-regulators. We also explore several clinically relevant aspects of the molecular biology of the androgen receptor and its co-regulators.

Keywords: Androgens, Androgen receptor, Molecular biology, Sex hormones

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PII: S0378-5122(09)00097-8

doi:10.1016/j.maturitas.2009.03.008

Maturitas
Volume 63, Issue 2 , Pages 142-148, 20 June 2009